Clozapine Powder is a light yellow crystalline powder in appearance. Odorless. Tasteless. Molecular weight 326.83. Melting point 183~184℃. Clozapine CAS 5786-21-0 is a non-classical antipsychotic that selectively blocks DA receptors in the limbic system of the midbrain and has less effect on DA receptors in the striatum nigra.Клозапин порошок (CAS 5786-21-0) субстанция ФС
Clozapine Raw Material has a potent sedative-hypnotic effect due to its ability to directly inhibit the upward activation system of the midbrain reticular formation. Clozapin Pulver (CAS 5786-21-0) Wirkstoff
Clozapine Raw Material is used in schizophrenia and is more effective in hallucinations, delusional symptoms and adolescent type.Clozapin Pulver (CAS 5786-21-0) Wirkstoff
Clozapine Powder is effective for positive symptoms such as euphoric agitation and hallucinatory delusions, but also for negative symptoms. Since, Clozapine CAS 5786-21-0 has a different mechanism of action than classical antipsychotics in blocking DA receptors, it may be effective in patients who do not respond well to classical antipsychotics. Clozapina pó (CAS 5786-21-0) insumo farmacêutico
Clozapine CAS 5786-21-0 may also be used for manic episodes and to improve intractable sleep disorders. In addition, it also has anticholinergic effect, NE blocking effect, sympathetic blocking effect, muscle relaxation effect and antihistamine effect.Clozapine poudre (CAS 5786-21-0) substance active
Uses and functions of Clozapine Powder.
1. For acute and chronic epilepsy. It is used for the symptoms of trance, confusion, dreaming, sadness and weeping, palpitations and panic, physical fatigue, sudden onset of illness, sudden rage and ignorance, and angry eyes.
2. It is used for all kinds of madness caused by various reasons. Such as impetuous temperament, or house destruction and beating, or crying and laughing erratically, emotional anxiety, tension, and sometimes mania.
3. Used for behavioral disorders of mental retardation. Such as delayed speech development, poor expression ability, slow thinking and comprehension, lack of abstraction and generalization ability. Slow perception, narrow perceptual range, difficulty in distinguishing small differences in the shape, size, and color of objects. Attention is not focused, and the breadth of attention is significantly narrow. Poor memory, slow speed of recognition and inaccurate reproduction. Childish, immature, emotionally unstable behavior, lack of self-control, and impulsivity. They are often timid, withdrawn, shy, and withdrawn. Unproportional body shape, motor uncoordination, poor flexibility, or show excessive activity, destruction, aggressive behavior or other undesirable behavior, etc.
4. for drug or alcohol dependence withdrawal syndrome. Such as acute tremor, agitation, easy jumping, nausea, vomiting and sweating. The symptoms disappear immediately once the alcohol is consumed, otherwise they last for several days. In some cases, there are transient delusions, hallucinations and distortions of vision and slurred pronunciation. Eventually there may be seizures or delirium tremens.
5. For sleeplessness. It is used for various manifestations of sleeplessness, such as dreaminess and wakefulness, palpitation and forgetfulness, tiredness and fatigue of limbs.
Pharmacological Effects of Clozapine Powder.
1. Antipsychotic effect: Clozapine is effective against various types of acute and chronic psychosis, relieving psychotic symptoms such as excitement, agitation, hallucinations, delusions, thought disorder, depersonalization, and peculiar movements. The mechanism of action may be related to blocking dopamine receptors in the limbic system of the midbrain, but does not affect dopamine receptors in the striatum, so the product rarely produces extrapyramidal reactions.
2. Sedative-hypnotic effects: small doses of this product can inhibit spontaneous activity, and large doses can increase spontaneous activity. Clozapine can directly inhibit the mesencephalic reticular upstream activation system.
3. Anticholinergic, antihistamine and antiepinephrine effects: This product has a strong anti-acetylcholine effect, and also has a blocking effect on histamine, norepinephrine and epinephrine.
Clozapine Powder is one of the strong tranquilizers and has good therapeutic effect on both acute and chronic schizophrenia. Its mechanism of action may be that it exerts pharmacological effects on the central dopamine nerve, selectively blocking dopamine receptors in the limbic system of the midbrain, with less effect on dopamine receptors in the substantia nigra striata, so it has a strong antipsychotic effect, while extrapyramidal adverse effects are rare. It does not depend on the functional activity of adenylate cyclase either.
Why Choose Our Clozapine Powder?
GMP Compliant Manufacturing
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Frequently Asked Questions
Q: What is the difference between Clozapine and Risperdal Powder?
A: Clozapine has a higher 5-HT2A/D2 binding rate and a lower extrapyramidal risk, but requires blood monitoring
Q: What is the minimum order quantity?
A: Typically 10 grams for research use, 100 grams or more for pharmaceutical use
Q: What are the polymorphic forms?
A: Type I (most stable) and Type II - please specify when ordering
Q: Is documentation provided?
A: Full COA, MSDS and CofA per lot
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