Pharmaceutical Raw Materials Amlodipine Besylate Powder CAS 111470-99-6 API Factory Supply

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Amlodipine Besylate Powder Usage and Synthesis.

Amlodipine Besylate, domestic trade name Lovoxil, its chemical name is 3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulfonate, Amlodipine Besylate Powder is used for cardiovascular diseases such as hypertension, angina pectoris and congestive cardiac arrest,

Amlodipine Besylate Raw Materials is unanimously recommended by the Cardiorenal Advisory Committee of the FDA for the treatment of hypertension.Amlodipine benzenesulfonate, also known as lorazepam and amlodipine, is a common medication for the treatment of hypertension and angina pectoris in our clinic today.

Uses and functions of Amlodipine Besylate Powder.

Amlodipine benzenesulfonate is a dihydropyridine calcium antagonist, which can effectively inhibit the transmembrane inward flow of calcium ions in the myocardium and vascular smooth muscle, and reduce blood pressure by directly dilating vascular smooth muscle. 

It has prominent effect on peripheral blood circulation and strong selectivity on blood vessels, which can diastole coronary arteries and systemic blood vessels. Increase coronary blood flow and reduce blood pressure. In vivo there is a weak negative inotropic effect on the human sinus node, atrioventricular node has no effect.

Pharmacological Effects of Amlodipine Besylate Powder.

Amlodipine benzenesulfonate, also known as luoxi and amlodipine, is a common drug for the treatment of hypertension and angina pectoris in our clinic, belonging to the calcium channel blockers, which can play an anti-hypertensive role by blocking the transmembrane entry of calcium ions into the myocardium and the vascular smooth muscle cells, and by directly relaxing the vascular smooth muscle, and is clinically used alone or in combination with other anti-hypertensive drugs for the treatment of essential hypertension.

The mechanism of action for the treatment of chronic stable angina and variant angina has not been fully determined, but it can relieve angina by dilating small peripheral arteries and coronary arteries, reducing total peripheral vascular resistance, relieving spasm of coronary arteries, lowering the afterload of the heart, and decreasing the heart's energy consumption and demand for oxygen.

Production method of Amlodipine Besylate Powder.

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