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Fusidic Acid Powder is also known as Clostridial Acid, Sodium Fusidic Acid, Sodium Clostridial Acid, Fusidomycin or Steroidal Acidomycin.Fusidine Powder is a clostridial acid antibiotic with a steroidal skeleton, Whose mechanism of action is to inhibit bacterial protein synthesis, and act as a bacteriostatic or bacteriostatic.
Fusidic Acid Raw Materials also have some antibacterial effects on certain Fusidic Acid Raw Materials also has a certain antibacterial effect on some Gram-negative bacteria. Fusidic Acid Raw Materials also has a certain antibacterial effect on some Gram-negative bacteria.
Uses and functions of Fusidic Acid / Fusidine Powder.
Clinical application is usually made into sodium salt, the molecular formula of sodium salt is C31H47NaO6. fusidic acid is highly sensitive to all kinds of Gram-positive cocci associated with skin infections, especially staphylococci, and is also effective against drug-resistant Staphylococcus aureus, and also has a certain degree of antimicrobial effect on some Gram-negative bacteria. No cross resistance with other antibiotics
Fusidic acid (Fusidate), Fusidium coccineum is a steroidal bacteriostatic antibiotic with no corticosteroid effect.Fusidic acid inhibits bacterial growth by blocking the release of translation elongation factor G (EF-G) from ribosomes.
Pharmacological Effects of Fusidic Acid / Fusidine Powder.
It has strong antibacterial effect on staphylococci (including methicillin-resistant strains or other antibiotic-resistant strains), and also has certain antibacterial effect on streptococci, enterococci, diphtheria bacilli, clostridium difficile, Neisseria spp. and tuberculosis bacilli, and has a weaker effect on bacilli of fragile mimicry.
Gram-negative bacteria, except Neisseria gonorrhoeae, Neisseria meningitidis, Clostridium difficile, and Mycobacterium fragilis are sensitive to the product, and all others are resistant to the product. In vitro, staphylococci are highly resistant to the product. There is no cross-resistance between this product and other anti-infective drugs.
Production method of Fusidic Acid / Fusidine Powder.
Sodium fusidic acid may be used in combination with penicillinase-resistant penicillins, cephalosporins, erythromycin, aminoglycosides, lincomycin, rifampicin, or vancomycin with additive or synergistic effects.
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