3-Carbamoymethyl-5-methylhexanoic Acid API Raw Material

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3-Carbamoymethyl-5-methylhexanoic Acid Uses and synthesis methods:
Uses 3-(carbamoyl methyl) -5-methylhexanoic acid is a pregabalin, a GABA analogue used as an intermediate in anticonvulsants. Uses As an intermediate in the synthesis of pregabalin.
Melting point :106-108°C
Predicted Boiling point :401.9±28.0°C
Density :1.080±0.06g/cm3(Predicted)
Storage conditions: Sealedindry RoomTemperature
Methanol DMChemicalbookSO(Slightly),Methanol(Slightly),Water(Slightly)
Form Solid
Predicted Acidity coefficient (pKa)4.68±0.10
The color is WhitetoOff-White

3-(carbamoyl methyl) -5-methylhexanoic acid is a pregabalin, a GABA analogue used as an intermediate in anticonvulsants. Uses As an intermediate in the synthesis of pregabalin. Pregabalin is used to treat neuralgia after herpes zoster and fibromyalgia, which is used to improve neuralgia. Pregabalin has a high affinity with the corresponding sites in the central system. The mechanism of action of pregabalin is still unclear.
Studies have shown that pregabalin may reduce the calcium-dependent release of some neurotransmitters by regulating the function of calcium channels, and play an analgesic effect. It is a structural derivative of the inhibitory neurotransmitter γ-aminobutyric acid, but it does not directly bind to γ-aminobutyric acid receptors, nor does it bind to benzodiazepine receptors. Therefore, the mechanism of action remains to be further investigated. Clinically, it is mainly used to improve neuralgia and fibromyalgia, and can also be used for the treatment of neuropathic pain.

Xi'an Henrikang Biotech Co., Ltd., located in Xi'an City, Shaanxi Province, China.  A professional researcher and one of the biggest manufacturer in pharmaceutical raw materials field. Henrikang Biotech is specialized in Research, Analysis, Production, Application, Produce and Sales. It has absolute advantage because of strong research strength, Advanced production facilities, modern management system and Experienced sales team. Henrikang insist in innovation and produce high quality products. And we have three GMP standard workshops and chemical synthesis equipments. 

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