(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid

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(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Powder Uses and synthesis methods:
(R)-(-)-3-(carbamoyl methyl) -5-methylhexanoic acid is solid at room temperature and pressure, soluble in dimethyl sulfoxide,N, n-dimethylformyl Chemicalbook amine and other organic solvents; It has poor solubility in ether solvents and can be used as intermediates in chiral organic synthesis. In the literature, diethyl ether is often used as a solvent for recrystallization and purification.
(r)-(-)-3-carbamoylmethyl-5-methylhexanoic Acid Powder is an intermediate in chiral organic synthesis, mainly used as a molecular framework to participate in the synthesis of chiral drug molecules and bioactive molecules. (R)-(-)-3-(carbamoyl methyl) -5-methylhexanoic acid can undergo lacamidation under appropriate conditions to produce the chiral (R) -3-isobutylglutarylimide.
For the synthesis of (R)-(-)-3-(carbamoyl methyl) -5-methylhexanoic acid, the conventional synthesis method is to start from the corresponding ester compounds and obtain the target product through the ammonia transesterification reaction under certain conditions, and then adjust the reaction system into acidity by adding acid such as hydrochloric acid. That is, you get the target product (R)-(-)-3-(carbamoyl methyl) -5-methylcaproic acid. It should be noted that the route needs heating reaction effect will be better.
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