Guanidine hydrochloride Raw material powder

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Guanidine hydrochloride Powder Usage and Synthesis.

It can be used as intermediates in medicine, pesticides, dyes and other organic synthesis. It can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4, 6-dimethylpyrimidine, and is an intermediate in the manufacture of sulfadiazine, sulfadimethyrimidine, sulfadimethyrimidine and other sulfonamide drugs. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2, 4-diamino-6-hydroxypyrimidine, which is used to synthesize folic acid, an antianemia drug. It can also be used as an antistatic agent for synthetic fibers.

Uses of Guanidine hydrochloride.

Guanidine hydrochloride is a strong ionic protein denaturant. As a protein denaturant, it can dissolve some insoluble or denatured proteins, such as endosomes; It can also be used for the initial folding of active proteins or enzymes; As a strong denaturant in the experiment of extracting total RNA from cells. Because of its biological destructive properties, buffers containing guanidine hydrochloride or guanidine thiocyanate are often called dissociated buffers.

Pharmacological action of Guanidine hydrochloride.

This product is a broad spectrum bacteriostatic agent, high concentration has bactericidal effect. This product has certain antibacterial effects on Streptococcus pneumoniae, hemolytic streptococcus, Chlorococcus aureus and some staphylococcus, Bacillus perculosus, Bacillus anthracis, Bacillus pestis, Bacillus diphtheria, Bacillus tetanus, Brucella, Haemophilus influenzae, Campylobacter and Vibrio cholerae. It also has inhibitory effects on Rickettsiae, mycoplasma, Chlamydia, spirochaetes and some protozoa. Enterobacteriaceae bacteria such as Escherichia coli, Klebsiella, Salmonella, Shigella and so on most of the drug resistance.

Product Method of Bulk Guanidine hydrochloride Powder.

Using dicyandiamide and ammonium salt (ammonium chloride) as raw materials, guanidine hydrochloride was melted at 170-230℃, and the finished product was obtained by refining.

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