Artemisinin Raw Material Powder

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Use and synthesis of Artemisinin :
Artemisinin 99% Powder is one of the most effective drugs to treat malaria. Artemisinin is a sesquiterpene lactone drug with peroxide group extracted from the stems and leaves of Artemisia annua.Artemisinin Manufacturers in China The effect of the drug on the ultrastructure of Plasmodium plasmodium in the red phase is mainly the change of the structure of plasmodium membrane. The drug first acts on the food vesicles, surface membranes, mitochondria, endoplasmic reticulum, and also has a certain effect on the chromatin in the nucleus.

The sesquiterpene lactone drugs with peroxy groups are extracted from Artemisia annua, a traditional Chinese medicine. At present, the curative effect of artemisinin-based combination therapy (ACT) for malaria treatment has reached more than 90% globally, and it has been widely used in the treatment of malaria in the world. At the same time, coccidiosis of chicken,

vivax malaria, porcine epigenetoplasmic jaundice, toxoplasmosis, Yin deficiency fever, falciparum malaria, cerebral malaria and anti-chloroquine malaria have outstanding effects. It has the characteristics of high efficiency, quick effect, clearing heat and relieving heat, eliminating deficiency heat, killing protozoa and low toxicity. It has a strong and rapid killing effect on the internal phase of Plasmodium red, and can quickly control clinical attacks and symptoms. Artemisiaannua, a plant in the composite family, has long been known for its ability to reduce fever.

Artemisinin, a drug developed in China that has proved effective in treating diseases such as malaria, and several other derivatives of artemisinin have recently gained popularity in Southeast Asia, where the malaria parasite has developed resistance to most anti-malarial drugs. Thousands of years ago, the Chinese used wormwood to treat malaria. Artemisia annua is a key drug in the fight against malaria, and it has become the world's first choice antimalarial drug. Artemisinin drugs have saved 10 million lives worldwide since they were introduced in the late 1970s.

Uses of artemisinin:
Artemisinin is used as an antimalarial drug. Clinical application has proved that artemisinin and its derivatives have special effects on malaria and falciparum malaria, especially Artemisinin (Artemisinin), which is stronger than other artemisinin-based drugs in reducing plasmodium plasmodium intracellular asexes. It has the advantages of high efficiency, quick effect, low toxicity and no cross resistance to chloroquine.

It can not only be used for treatment, but also for first aid. It is suitable for all kinds of malaria, such as falciparum malaria, vivax malaria, chloroquine-resistant malaria and cerebral malaria. Including the dangerous type. The most notable is dihydroartemisinin and its tablets. The drug was 10 times more effective against malaria than artemisinin, with a recurrence rate of only 1.95%.

Therefore, it was named as one of China's top ten scientific and technological achievements in 1992. Artemisinin and its derivatives are not only an excellent antimalarial drug, but also potentially attractive for the treatment of other diseases. In animal experiments, artemisinin was used to treat clonorchis sinensis in mice, and the eradication rate could reach 100%.

For the treatment of schistosomiasis in animals, the pest control rate reached 33.8-99.3%. Artemisinin was used to treat discoid lupus erythematosus, and the total effective rate was 90%. In the treatment of dengue fever, the curative effect is significantly better than that of western drugs such as morpholine biguanide. Immunologists also found that artemisinin can significantly improve the conversion rate of lymphocytes and enhance the immune function of antibodies. No toxic effects were found on the heart, liver and kidney. There were no obvious side effects in clinic.

Melting point: 156-157°C(lit.)
Specific rotation: 76º(c=0.5,MeOH)
Boiling point: 344.94°C(roughestimate)
Density: 1.0984(roughestimate)
Refractive index: 75°(C=0.5,MChemicalbookeOH)
Storage condition: -20°C
Solubility: Solubleto100mMinDMSOandto75mMinethanol
Mode: Whitetooff-whitecrystallinesolid.
Color: Needles

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