Acetylsalicylic Acid Raw Material Powder

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Use and synthesis of Acetylsalicylic Acid :

Aspirin, also known as acetylsalicylic acid, belongs to the class of non-steroidal anti-inflammatory drugs, the earliest used for anti-inflammatory and analgesic.

Scientists later discovered that aspirin prevented platelets from clumping together, thus preventing blood clots. As research on aspirin continues, many new uses have been found, such as reducing death rates from heart attacks and strokes, and reducing the risk of colorectal cancer.

Pharmacological effects of Acetylsalicylic Acid :
Acetylsalicylic acid (aspirin) is a traditional antipyretic and analgesic drug. The mechanism of acetylsalicylic acid (aspirin) is to acetylate the epoxide of platelets, thus inhibiting the formation of intra-ring peroxide and reducing the generation of TXA2.

It also has the effect of anti-platelet aggregation. It is suitable for ischemic heart disease. After PTCA and coronary artery bypass grafting, it can prevent transient cerebral ischemia, stroke and myocardial infarction, and reduce the incidence of arrhythmia.

Acetylsalicylic acid (aspirin) has antithrombotic properties in vivo and can reduce the formation of obstructive thrombus in peripheral arteries.

Inhibition of platelet release response and endogenous ADP, 5-HT and so on. Therefore, the second phase of platelet aggregation was inhibited without the first phase of platelet aggregation. Acetylation of platelet membrane proteins and inhibition of thrombocytopenase, which also helps to inhibit platelet function.

Because of the inhibition of cyclooxygenase, the synthesis of PGI2 in vascular wall was affected. It can also inhibit the enzyme of platelet TXA2 synthesis, such as the production of TXA2 and PGI2 at large doses.

Indications of aAcetylsalicylic Acid :
Acetylsalicylic acid, also known as aspirin, is antithrombotic: this product has an inhibitory effect on platelet aggregation and can prevent thrombosis.

It is clinically used to prevent thrombosis after transient ischemic attack, myocardial infarction, atrial fibrillation, artificial heart valve, arteriovenous fistula or other operations.

It can also be used to treat unstable angina. The clinical application of acetylsalicylic acid is also called aspirin as an antiplatelet aggregation drug.

It can inhibit platelet aggregation and prevent thrombosis. It is used to prevent transient ischemic attack, myocardial infarction, arterial thrombosis and atherosclerosis. In addition, it can also treat biliary ascariasis.

Acetylsalicylic Acid  uses:
Poplar acid and acetic acid. Slightly soluble in water, soluble in ethanol, ether, chloroform, but also soluble in hydroxide alkali solution or carbonic acid solution, at the same time decomposition. A commonly used antipyretic and analgesic.

It is used for relieving fever, analgesia, anti-rheumatism, promoting uric acid excretion in gout patients, anti-platelet aggregation and treatment of biliary ascaris.

Acetylsalicylic acid is used in the manufacture of outdoor and strong light irradiation of structural parts, equipment parts, such as automobile body, agricultural machinery parts, electricity meters and lampshade, road markings and other uses of antipyretic and analgesic drugs, for fever, pain and rheumatoid arthritis and other uses is the earliest, most widely used and the most common antipyretic, analgesic and antirheumatic drugs.

It has many pharmacological effects, such as antipyretic, analgesic, anti-inflammatory, anti-wind mild and anti-platelet aggregation, and plays a rapid and positive role.

Overdose is easy to diagnose and treat, and allergic reactions rarely occur. It is often used for cold and fever, headache, neuralgia, arthralgia, muscle pain, rheumatic fever, acute moist arthritis, rheumatoid arthritis and toothache. Acetylsalicylic acid is listed in the National Essential Medicine List and is also an intermediate of other drugs.

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