Moxonidine Raw Material Moxonidinum Powder

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Moxonidine Raw Materials Usage and Synthesis

Manufactory Supply Moxonidine Raw Powder High Quality Moxonidine Raw Material , High Purity 99% Moxonidine Powder CAS 75438-57-2 Moxonidine Raw Powder. Moxonidine Powder belongs to a new class of antihypertensive drugs commonly used in the treatment of essential hypertension.

Uses and functions of Moxonidine Powder

Moxonidine, also known as Moxonidine, chemically known as 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine, is a highly selective imidazoline-type I receptor agonist, which reduces peripheral sympathetic activity by agonising the ventral ventral lateral nucleus of the medulla oblongata (RVLM)-Imidazoline-type I receptor, thus relaxing the vasodilatation and decreasing peripheral resistance to vascular resistance so that the blood pressure decreases, and it belongs to a new type of antihypertensive drug, which is commonly used in the treatment of essential hypertension.

• 1. It works by stimulating central presynaptic α2-receptors. Its antihypertensive effect is similar to that of the calcium antagonist nifedipine and the ACE inhibitor captopril. It is used in essential hypertension.   
• 2. Interferes with renal interstitial fibrosis and thus protects the kidneys.
• 3.Acts by stimulating central presynaptic α2-receptors. Its antihypertensive effect is similar to that of the calcium antagonist nifedipine and the ACE inhibitor captopril. It is used in essential hypertension.

Pharmacological Effects of Moxonidine Raw Powder

• The reaction of 5-amino-4,6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolidin-2-one yields moxonidine by the action of the resulting product and sodium methanol.
• Production method of Raw Moxonidine Powder
• Method 1: Reaction of 5-amino-4,6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolidin-2-one, the resulting product and sodium methanolate yielded moxonidine.
• Method 2: Reaction of 5-amino-4-chloro-6-methoxy-2-methylpyrimidine with ammonium thiocyanate and benzoyl chloride to give (I). De-benzoylated to give (II), methylated to give (III), and then interacted with ethylenediamine to give moxonidine.

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