Vitamin B2 Raw Materials powder

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Vitamin B2 powder Usage and Synthesis.

Vitamin B2 (riboflavin) is a water-soluble vitamin that is easily digested and absorbed, and the amount excreted increases or decreases according to the body's needs and possibly the degree of protein loss; it does not accumulate in the body, so from time to time it must be replenished with food or nutritional supplements.

Unlike vitamin B1, vitamin B2 is resistant to heat, acid and oxidation. Clinically, vitamin B2 tablets are used for the prevention and treatment of vitamin B2 deficiency, such as keratitis, dry and cracked lips, laryngitis, scrotal inflammation, conjunctivitis, seborrheic dermatitis, etc.; can also be used for the whole gastrointestinal tract outside the nutrition and insufficient intake of malnutrition caused by the treatment of malnutrition, progressive weight loss, etc.

Uses of Vitamin B2 powder.

Riboflavin exists in green vegetables, soybeans, rice, wheat, yeast, liver, heart and dairy, riboflavin in the body is distributed in the tissues, constituting a coenzyme in the body in the system of hydrogenation of the complementary hydrogenation, participate in redox reactions, play a role in the transmission of hydrogen atoms.

When riboflavin deficiency, it will affect the biological oxidation, so that the metabolism is impaired, resulting in lesions occurring in the mouth, eyes, external genitalia, such as stomatitis, labyrinthitis, conjunctivitis, scrotal inflammation and so on.

Riboflavin is mainly used as medicine, food additives and feed additives, in the medicinal aspect, used for multivitamin or vitamin B2 preparations, but also used as sugar-coated tablets and capsules of yellow coloring agent. When used as food additives, on the one hand, it has the effect of strengthening nutrition, on the other hand, it is also used as yellow coloring agent. The LD50 for intraperitoneal injection in rats is 560mg/kg.

Biochemical research, used as photocatalyst for acrylamide gel polymerization, nutrient, clinical drug belongs to the vitamin B family, involved in the body of sugar, fat, protein metabolism, to maintain normal visual function, and promote growth. Clinical use for the treatment of vitamin B2 deficiency caused by keratitis, lingual inflammation and other conditions.

In vitro studies of Vitamin B2 powder.

Product Method of Bulk Vitamin B2 powder.

Vitamin B2 is naturally found in the liver and kidney of animals, as well as in meat and dairy and other foods, and is produced industrially by fermentation and chemical synthesis methods.

Fermentation

Take glucose, corn syrup, inorganic salt, etc. as the culture medium, and use special active bacterium, Pseudocystis aristolochiae (Eremotheciumashbyii), to cultivate the deep fermentation at 28℃ for 9d, and the fermentation liquid contains about 6~8g/L riboflavin products. The extraction yield is 60% to 70%.

Synthesis method

The better synthesis method is first in Ph = 4 and 28 ~ 30 ℃ by 3,4-dimethylaniline and D-ribose condensation, and then nickel-catalyzed hydrogenation reduction of ribonucleamide, and then coupled with aniline diazonium salt at 16 ~ 26 ℃, and then reduced with sodium hyposulfite (insurance powder), and finally in acetic acid and barbituric acid (tetroxine) cyclic synthesis of vitamin B2

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