HRK Supply Iron Fumarate raw Materials powder Iron Fumarate

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Iron Fumarate Powder Usage and Synthesis.

Ferrous fumarate is absorbed in animals in the form of ferrous ions in the duodenum and upper jejunum. Most of the absorbed iron is involved in the synthesis of haemoglobin in the bone marrow, while the remainder is stored as ferritin and ferric haemoflavin in the reticuloendothelial cells of the bone marrow, liver and spleen, and a further part is present in the cells of the intestinal mucosa.

This absorption method is different from inorganic iron supplements (ferrous sulfate, ferrous carbonate and iron oxide, etc.), which can alleviate the competitive antagonism between the absorption of Chemicalbook trace elements, will not destroy the vitamins, and will not catalyse oxidation reactions, and the nutrients with a good compatibility, and can smoothly pass the body absorption barrier, which not only greatly improves the absorption and utilisation rate of iron, but also improves the absorption rate of other elements.

Iron is excreted mainly through the intestinal tract and the skin, with small amounts also excreted in the urine and sweat glands. Most of the iron can be reused when it is released after the haemoglobin molecule is destroyed.

Uses of Iron Fumarate.

Ferrous fumarate is an anti-anaemic drug. Anaemia is divided into iron deficiency anaemia, megaloblastic anaemia and aplastic anaemia according to the different causes, ferrous fumarate is used for the treatment of iron deficiency anaemia, with high iron content, good absorption, difficult to be oxidized to trivalent iron, the serum iron value rises very quickly after serving and can be kept stable. The oral LD50 of mice is 480mg/kg.

Ferrous fumarate as food iron fortifier, absorption effect is better than inorganic iron. Our country stipulates that it can be used in table salt and sandwich sugar, and the usage rate is 1800-1600mg/kg; 520-580mg/kg in high iron cereals and their products (daily limit of 50gfor this kind of food); 180-300mg/kg in dairy products and baby food; 70-150mg/kg in cereals and their products; 30-60mg/kg in In beverages 30-60mg/kg.

Pharmacological effect of Iron Fumarate.

Product method of Bulk Iron Fumarate Powder.

It is obtained by replacing sodium transbutylene diacid with ferrous sulphate. Heat water to boiling, add transbutylene succinate with stirring, add sodium carbonate to pH=6.5-6.7 in stages, stir well and filter while hot, get sodium transbutylene succinate solution. Add ferrous sulfate solution, stirring and heating reflux 3-4h, cooling crystallisation, shake filter. The filter cake is washed with distilled water until the sulfate meets the requirements, dry, get ferrous fumarate, yield 83%.

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