Chloramphenicol Raw Material Powder
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Introduction to chloramphenicol:Chloramphenicol is an antibiotic anti-infective raw material, Chloramphenicol Powder CAS 56-75-7 White Powder, China Supplier and Manufacturer wholesale Chloramphenicol Raw Material Powder in China Factory.
Chloramphenicol, also known as chloramphenol, is a broad spectrum antibiotic produced by Streptomyces chloramphenicol that has the effect of inhibiting bacterial growth. Natural chloramphenicol is levomycin (also known as levomycin). Chloramphenicol Raw Material Powder is white or yellowish needle-like or flaky crystal, odorless and extremely bitter. Chloramphenicol is slightly soluble in water, ether and chloroform, easily soluble in methanol, alcohol, acetone or ethyl acetate, but insoluble in benzene and petroleum ether. In neutral or weak acid aqueous solution is more stable, easy to fail in alkali. The resultant product is racemate, also known as synthycin. Synthicin is a mixture of left - and right-handed chloramphenicol. Because dextromycin has no antibacterial effect, the efficacy of synthycin is only half that of natural products.
Chloramphenicol powder can inhibit gram-negative bacteria and Gram-positive bacteria, and can be used to treat diseases such as typhoid dysentery, urinary tract infection, whooping cough, pneumonia and sepsis. But it is harmful to the liver. The method and dosage should be strictly followed the doctor's advice. Chloramphenicol palmitate is insoluble in water, oral odorless, also known as odorless chloramphenicol. Chloramphenicol works by inhibiting bacterial protein synthesis. When ingested, chloramphenicol is released through lipolysis and enzymatic hydrolysis in the small intestine. Unscented chloramphenicol contains about 60% chloramphenicol, so the dose should be increased by 2/3. It is especially suitable for children. A 1% ointment containing chloramphenicol can be used to treat eye and skin infections. In agriculture, it is mainly effective against plant bacterial diseases, such as rice leaf blight.
Chloramphenicol use:1. Chloramphenicol powder is the preferred drug for typhoid and paratyphoid, and can be used for typhoid and salmonella infections.
2. Chloramphenicol powder is used for ampicillin-resistant influenza-B meningitis or pneumococcal meningitis, meningococcal meningitis, and Gram-negative bacterial meningitis in patients allergic to penicillin.
3. Chloramphenicol powder was used for otogenic brain abscess caused by mixed aerobic and anaerobic bacteria.
4, severe anaerobic bacterial infection, such as fragile bacilli infection.
5. Chloramphenicol powder can be combined with aminoglycosides to treat various infections caused by sensitive bacteria and other microorganisms, such as sepsis and pulmonary infection caused by influenzae, salmonella and other gram-negative bacilli.
6. It is used locally to treat superficial eye and ear infections caused by Escherichia coli, influenzobacter, Klebsiella, Staphylococcus aureus and hemolytic streptococcus.
7. Chloramphenicol powder was also effective against Rickettsia, mycoplasma and all infections.
8. Chloramphenicol powder was not effective against Pseudomonas aeruginosa and Serratia.
9. Chloramphenicol powder drops are used to treat eye infections caused by sensitive bacteria, such as trachoma, conjunctivitis, keratitis and blepharmitis.
10. The local ear drops of this medicine can be used to treat otitis externa and acute and chronic otitis media caused by sensitive bacterial infection. The ear plugs of this medicine can also be used for otitis and abscess discharge after radical mastoidectomy.
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