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Xianhecao extract is a constituent extracted from the Rosaceae plant Longbudao, which has a variety of pharmacological effects. According to the research, Cranesbill extract has anticancer effects, with strong inhibitory effects on human cervical cancer cells and a variety of mouse tumour cells.
In addition, Cranesbill extract has a cardiotonic effect. In clinical practice, centella asiatica extract has been used to treat thrombocytopenic purpura, anaphylactic purpura, chronic dysentery with colitis and other diseases.
It is worth noting that Cranesbill extract has a growth-promoting effect on normal human cells, so the dosage and indications for use should be strictly controlled.
Uses and functions of Agrimory Extract.
Xianhe Cao can stop bleeding by astringency, stop malaria, stop dysentery, detoxification, clinically used for coughing up blood, bleeding, leakage of blood, malaria, bloody diarrhoea, exhaustion and strain, carbuncle, swelling and sores, itchy vagina and bring down the blood.
It has anti-tumour, hypoglycaemic, analgesic and anti-inflammatory, haemostatic, hypotensive, anti-malarial, anti-arrhythmic, insecticidal and other pharmacological effects.
Pharmacological Effect of Agrimory Extract Powder.
1.Haemostatic effect
Xianhecao crude extract has the effect of promoting blood coagulation, frog leg perfusion has the effect of contraction of peripheral blood vessels, with Xianhecao pigment to mice after static injection, bleeding time is shortened by 45%; to rabbits static injection, it can greatly shorten its blood coagulation time, and make the number of platelets increased, in addition to this product there is an inhibition of fibrinolytic enzyme effect.
Experimental dog femoral artery haemorrhage, local application of this product powder and compression also has a certain haemostatic effect. Experimental and clinical evidence of haemostatic effective component is cynarin. But there are also negative results reported.
2. Antibacterial and antiparasitic effects
The hot water or ethanol infusion of Cynomolgus has certain inhibitory effect on Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Fusarium dysentery, Typhoid fever bacillus, and human tuberculosis bacillus in vitro.
The decoction of its young stems and leaves applied locally has the effect of inhibiting and killing vaginal trichomonas. This product also has inhibitory effect on schistosomes, Plasmodium berghei.
3. Anti-inflammatory, analgesic effect
The aqueous extract and alcoholic and aqueous extracts of Fructus Xianhecao have good anti-inflammatory effect on experimental conjunctivitis. Its aqueous extract and alcohol, water extract have significant analgesic effect.
4.Anti-cancer effect
The 1:1 solution of the aqueous and alcoholic precipitation method of Cynoglossum has good inhibitory effect on mouse sarcoma S180, cervical cancer 14, brain tumour 22, Ehrlich's ascites carcinoma, melanoma 16, and Wacker's carcinoma 256 in rats.
5.Other effects
Cynarin has the effect of increasing cell resistance and lowering blood sugar on experimental animals. Its alcohol-soluble leachate can excite the respiratory centre, a large number of respiratory first fast and then become exhausted.
Extraction method of Bulk Agrimory Extract Powder.
1.Water extraction method
Take 500g of cranesbill, put 5000mL round bottom flask, add water 3000mL reflux extraction 1.5h, filtration, residue and then add water 3000mL reflux extraction 2 times, each time 1h, filtration, filtration, combined filtrate, concentration, vacuum drying oven drying, get cranesbill aqueous extracts.
2. Alcohol extraction method
Take 300g of cranesbill, set 5000mL round bottom flask, add 90% ethanol 3000mL reflux extraction 2h, filtration, residue and then add 90% ethanol 2000mL reflux extraction 2 times, each time 1h, filtration, filtrate, combined filtrate, recovery of ethanol, concentrated to the concentration of 1g of raw materials / mL, plus an equal amount of pure water wash, wash a total of 3 times to the absence of ethanol flavour, drying in vacuum drying oven. The alcohol extract of Cynodon grandiflorum was dried in a vacuum drying oven.
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