Raw Materials Celery Extract Apigenin Powder

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Celery Extract Apigenin Powder Usage and Synthesis.

1. Clearing heat and calming the liver, used for dizziness and headache, red face and red eyes of hyperactivity of liver yang. Fresh celery juice can be added to the amount of honey and mix well, 3 times a day, 40ml each time, or 500g of celery decoction, add sugar moderate tea drink. Clinical use of this product for the treatment of hypertension, hypercholesterolaemia have certain efficacy.

2. Clearing away heat and dampness, used for urinary incontinence, dribbling and astringent pain, blood in urine and other evidence. The fresh product can be washed and mashed juice. Clinical use of concentrated decoction of this product for the treatment of celiac disease, the efficacy is remarkable. In addition, this product has the function of moistening the lung and relieving cough, which can be used for paediatric whooping cough or Yin deficiency labour cough.

Uses of Celery Extract Apigenin.

Clearing heat and removing vexation, calming the liver, inducing diuresis, subduing oedema, cooling the blood and stopping bleeding. It is used in treating hypertension, headache, dizziness, fever and thirst, jaundice, oedema, hot and astringent urination, menstrual disorders, scrofula, mumps and other diseases.

It is used for the liver meridian with heat, liver yang hyperactivity, disturbing heat, dizziness; feverish shower, turbid urine, urinary dysuria or blood in urine; menstrual pre-menstrual period; gastric heat and vomiting, dietary reduction. It is used in modern times for hypertension and celiac disease.

Pharmacological Effect of Celery Extract Apigenin.

1. Hypotensive effect

The crude extract of celery has obvious antihypertensive effect on rabbits and dogs injected intravenously, and its main active ingredient is the derivative of coumarin and furan coumarin, in addition to which, flavonoids such as apigenin, polygonum, 7-methyl polygonum and other flavonoids may also be the effective ingredient for the treatment of high blood pressure.

2.Lipid-lowering effect

Celery extract can significantly reduce the concentrations of serum total cholesterol, triglyceride, LDL-cholesterol and ApoE in hyperlipidaemic rats; significantly increase the concentrations of HDL-cholesterol and ApoA; significantly reduce the content of malondialdehyde in serum and liver, and enhance the activities of superoxide dismutase and glutathione peroxidase in serum and liver. Celery extract can also significantly reduce the atherosclerosis index.

3.Anti-cancer effects

Apigenin extracted from celery can effectively inhibit the growth of many kinds of cancer cells, such as human prostate cancer cells, ovarian cancer cells, breast cancer cells, stomach cancer cells.

4. Antioxidant

Celery extract is a natural antioxidant, with obvious antioxidant effect, can enhance antioxidant activity. It can eliminate excessive free radicals in the body and reduce the toxic side effects of free radicals.

5. Hepatoprotective effect

Celery root extract has a certain protective effect on acute liver injury caused by CCl4 in mice.

6.Sedative effect

Isolated from the celery seed of an alkaline component, sedative effect on animals, can enhance the anaesthetic effect of pentobarbital, with conditioned escape response and reduce the mortality rate of aniline group of mice experiments, suggesting that this alkaloid has a stabilising effect.

7.Bacteriostatic effect

Volatile oil has antibacterial effect on Pseudomonas spp. in vitro. The ether and acetone extracts of celery seeds have antibacterial effects.

8.Analgesic effect

Celery seed extract has contraction effect on pregnant and end-pregnant uterus, and can be used for dysmenorrhoea.

Preparation method of  Bulk Celery Extract Apigenin Powder.

Fresh celery washed, chopped, dried at 60 ℃, crushed to 80 mesh; 40% ethanol extracted at 60 ℃ for 3 times, the combined extract, concentrated under reduced pressure, vacuum freeze-dried to obtain celery extracts

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