Notoginseng Root Extract Raw Materials powder

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Notoginseng Root Extract Powder Usage and Synthesis.

‌ Health products and pharmaceutical field ‌ : LTD uses authentic Wenshan Notoginseng as raw material to produce various kinds of notoginseng saponin extracts, which are widely used in health products and pharmaceutical fields ‌. Panax Notoginseng extract has the effect of stopping bleeding, fixing pain and dispersing blood stasis. It is used to treat many diseases ‌.

‌ Cosmetic field ‌ : Panax notoginseng extract has an inhibitory effect on edema and nuclear factor receptor activation, which reflects its anti-inflammatory ability. In addition, Panax Notoginseng extract can eliminate oxygen free radicals, enhance the activity of endogenous superoxide dismutase, strengthen the body's scavenging ability of oxygen free radicals, reduce the chain reaction caused by oxygen free radicals, and reduce the peroxidation of lipids in blood. The antibacterial properties of Panax Notoginseng extract make it an ideal ingredient in cosmetics, providing multiple anti-inflammatory and antioxidant benefits ‌.

‌ Other applications ‌ : In personal care products, Notoginseng root extract acts as anti-inflammatory agent, antioxidant and antibacterial agent. It works in synergy with other ingredients such as snow lotus extract and peony branch/flower/leaf extract to provide moisturizing, anti-sensitizing and whitening functions. These ingredients are used in products such as DRPLANT Pure and Flawless Facial cleanser, demonstrating the versatility of ginseng root extract.

Use of Notoginseng Root Extract.

1, the impact on the blood and hematopoietic system: modern pharmacological studies have shown that Notoginseng extract not only has a good hemostasis, blood circulation and stasis removal two-way pharmacological effect, but also has a significant blood-tonification effect, can promote the blood of red blood cells, white blood cells, platelets and other blood cell division and growth, increase the number, and maintain a normal level.

2. Effects on cardiovascular and cerebrovascular system: reduce myocardial oxygen consumption, anti-arrhythmia, reduce blood lipids, lower blood pressure, improve cardio-cerebral blood circulation, reduce cardiovascular and cerebrovascular resistance, and increase cardio-cerebral blood flow.

3. Impact on the immune system: It can increase the function of mononuclear macrophage system, promote the weight gain of immune organs, thymus and spleen, and enhance the cellular and humoral immunity of the body.

4, the effect of material metabolism: it has a significant impact on sugar metabolism, blood lipids, proteins and nucleic acids.

5, the impact of the nervous system: calming, analgesic, intellectual effect, chemical and thermal stimulation caused by pain have obvious analgesic effect, its intellectual effect can significantly improve learning ability and memory.

6, liver protection: can increase liver tissue and serum content, reduce liver glycogen consumption, improve liver microcirculation, reduce mitochondria, endoplasmic reticulum and other organelles damage and liver fibrosis.

Pharmacological action of Notoginseng Root Extract.

1. The anti-inflammatory effect of water extract of Panax Notoginseng root by subcutaneous injection of 50 ~ 200mg/kg can inhibit the increase of skin vascular permeability caused by hyaluronidase, chondroitin enzyme ABC, α-chymotrypsin and histamine by 11% ~ 36%. The total saponins of Panax notoginseng, diagonalenin, kaolin, 5-hydroxytryptamine, egg white and hyaluronidase can inhibit the ankle joint swelling and foot swelling in mice or rats. In addition, the total saponins of panax notoginseng had obvious inhibitory effect on ear swelling induced by xylene and croton oil in mice.

2. Anti-tumor effect of Notoginseng saponin Rb1120μg/ml can inhibit 92% of tumor cells in culture, while only 29% of normal cells in culture are inhibited. Rd also has obvious inhibitory effect on tumor cells in culture. Saponin Rh1 also has an inhibitory effect on liver cancer cells in vitro, which directly acts on the cell membrane. Saponin Rh2 can inhibit the growth of mouse melanoma (B16) in a concentration-dependent manner and induce the redifferentiation of cancer cells into non-cancer cells.

3. Effect on immune function Notoginseng total saponins 160mg/kg can increase the number of hemolytic plaque in mice by 92%, and can also improve the phagocytosis rate and phagocytosis index of mouse peritoneal macrophages. It can significantly increase the phagocytosis rate of alveolar macrophages, increase the total number of white blood cells and the percentage of lymphocytes in blood, and reduce the migration index of white blood cells.

Product Method of Bulk Notoginseng Root Extract Powder.

Panax Notoginseng polyphenol extraction process Weigh 40g panax notoginseng root, crushed through a 40-mesh sieve, dried to constant weight in a vacuum drying oven, took 1g powder, placed it in a triangle flask, sealed with plastic wrap, placed it in a water bath, and extracted it according to the experimental design conditions. The extraction was repeated twice and combined with three extracts to obtain the total polyphenol extract.

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