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Fenbendazole Powder is a broad-spectrum, highly effective and low-toxicity benzimidazole anthelmintic, which has a strong structural affinity with the microtubule proteins of worms, and prevents the polymerisation of microtubules by affecting the transport and energy metabolism of the cells, and ultimately destroying the integrity and energy transmission of worms' cells.
Veterinary Medicine Fenbendazole is a broad-spectrum anthelmintic with the advantages of wide anthelmintic spectrum, toxicity generation, good tolerance, wide safety range, good palatability, etc. Fenbendazole Raw Materials is a veterinary anthelmintic which is widely used in foreign countries at present.
Uses and functions of Fenbendazole Powder.
Fenbendazole is a broad-spectrum, highly effective and low-toxicity benzimidazole anthelmintic, which has a strong structural affinity with microtubule proteins of worms, and prevents the polymerisation of microtubules by affecting cellular transport and energy metabolism, which ultimately destroys the cellular integrity of worms and the function of energy transmission.
Benzimidazole is used to kill gastrointestinal parasites in animals, it not only has high anthelmintic activity against gastrointestinal roundworms, hookworms, whipworms, some tapeworms and roundworms in animals, but also has a better efficacy against some parasites of the bronchial tree and the lungs (catarrhine worms and pulmonary schistosomiasis).
Antihelminthic. Broad-spectrum, highly effective, low-toxicity, anti-helminthic drug. It has strong anthelmintic effect on roundworms, nematodes, tapeworms, cysticerci and liver flake trematodes, etc. It not only kills worms, but also has great efficacy on migratory larvae, which are harmful to the liver, lungs and intestines. Fenbendazole is a benzimidazole anthelmintic, which not only has a high anthelmintic activity against gastrointestinal nematodes and larvae, but also has a good effect on nematodes, tapeworms and cestodes, as well as a strong ovicidal effect.
Pharmacological Effects of Fenbendazole Powder.
Fenbendazole Powder is a broad-spectrum anthelmintic with the advantages of wide anthelmintic spectrum, toxicity generation, good tolerance, wide safety range, good palatability and so on, and it is a veterinary anthelmintic which is widely used in foreign countries at present.
It is widely used in foreign countries. For adult and larval gastrointestinal nematodes in sheep, horses and pigs, a single oral dose of 3.5-5mg/kg can reduce 99-100% of the worms. The rate of reduction is 99-100% for liver flake trematode (20mg/kg) and Moniezia tapeworm (5-10mg/kg) in sheep.
Production method of Fenbendazole Powder.
From the reaction of 5-chloro-2-nitroaniline and phenylthiol, 5-phenylthio-2-nitroaniline was produced with 91% yield. 3-Phenylthio-o-phenylenediamine was reduced by ferrous sulfate-iron powder with 90% yield. Finally, the benzothiobenzimidazole was obtained by cyclisation with methyl S-methyl-cyanamidoformate.
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