Veterinary Medicine Rifampicin Powder CAS 13292-46-1 Raw Materials

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Product details

Rifampicin Powder Usage and Synthesis.

Rifampicin Powder (also translated: Lifamycin, Meperifamycin, Mepirifamycin, Weifuxian, Xian Daolun,) Veterinary Medicine Rifampicin is a broad-spectrum drug belonging to the rifamycin family Antibiotic drugs have a strong antibacterial effect on Mycobacterium tuberculosis, 

And Rifampicin Raw Materials are also effective against Gram-positive or negative bacteria and viruses. 

It is red or dark red crystalline powder, insoluble in water. Rifampicin Raw Materials are generally oral medicines in capsules or tablets, which work synergistically with other anti-tuberculosis drugs and delay the emergence of drug-resistant strains.

Uses and functions of Rifampicin Powder.

Broad spectrum antibiotic. It has bacteriostatic or bactericidal effects on Mycobacterium tuberculosis, Gram-positive bacteria and some Gram-negative bacteria.

Mainly used for drug-resistant tuberculosis phytobacteria and drug-resistant Staphylococcus aureus infections, also has a certain effect on leprosy. It is a broad-spectrum antibiotic, and can enter the cell, is a full-effect bactericidal drug, strong bactericidal force is a broad-spectrum antibiotic,

the divergent bacilli and Gram-positive and negative bacteria have a strong bactericidal effect Used as pharmaceutical intermediates have a broad-spectrum antimicrobial effect, Gram-positive coccobacilli, Mycobacterium tuberculosis has a good antimicrobial activity, the antimicrobial spectrum is the same as rifampicin

Inhibits recombination of DNA and protein insertion into mature viral particles. Inhibits the initiation of RNA synthesis by binding to the β-subunit of RNA polymerase.

Pharmacological Effects of Rifampicin Powder.

Orange-red flaky crystals or brick-red crystalline powder. Decomposes at 183-188°C. Freely soluble in chloroform and dimethyl sulfoxide, soluble in ethyl acetate, methanol and tetrahydrofuran, soluble in water (pH < 6), propanol and carbon tetrachloride.

Dry powder can be stable for more than 5 years, its aqueous solution at room temperature 10h failure, but the addition of reducing agents (such as anticyclamic acid) can reduce the decomposition, in dimethyl sulfoxide is very stable.

Production method of Rifampicin Powder.

Rifampicin is a semi-synthetic derivative of Rifamycin SV. Rifamycin SV is oxidised to rifamycin S, then formylated with formaldehyde and tert-butylamine to form 3-formyl tert-butylamine rifamycin S. Rifampicin is then obtained by reduction with vitamin C and condensation with 1-methyl-4-aminopiperazine.

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