Veterinary Medicine Aminophylline Powder CAS 317-34-0 Raw Materials

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Aminophylline Powder Usage and Synthesis.

Aminophylline Powder is a double salt composed of theophylline and ethylenediamine, which belongs to xanthine drugs. The pharmacological effects of Aminophylline Raw Materials are mainly derived from theophylline. 

Theophylline has the strongest effect on relaxing airway smooth muscle among xanthine alkaloid drugs. , Ethylenediamine can enhance its water solubility. 

Veterinary Medicine Aminophylline is suitable for the treatment of bronchial asthma, obstructive emphysema and asthmatic bronchitis. Therefore, it can also be used in the treatment of diseases such as asphyxia of premature infants, sick sinus syndrome, and acute lung injury.

Uses and functions of aminophylline powder.

It is suitable for asthmatic respiratory asthma, sleep apnea syndrome and premature breathing, chronic obstructive pulmonary disease and chronic obstructive pulmonary disease, and relieves asthmatic respiratory symptoms. It can also be used for acute cardiac insufficiency and cardiogenic symptoms.

• 1. Treatment of pulmonary hypertension: Aminophylline can directly change the Ca2+ concentration of the pulmonary artery wall and reduce Ca2+ outflow, inhibit PDE to relax smooth muscle, reduce pulmonary vascular resistance and pulmonary arterial pressure, reduce pulmonary vascular extravasation, and eliminate pulmonary edema.
• 2. Sleep treatment for apnea syndrome and premature infants: aminophylline promotes the release of catecholamine sympathetic neurotransmitters through the respiratory center, enhances diaphragm muscle contractility and hypoxic response, and is effective for sleep apnea. Step into adulthood. Excitement for premature infants Madagascar, prevention of hyperexcitability.
• 3. Prevention and treatment of drowsiness and respiratory depression after general anesthesia: aminophylline excites the central nervous system, lowers the threshold of respiration initiated by electrodes, increases responsiveness to pain, neurotomy function and muscle tension, and inhibits respiratory depression.
• 4. Treatment of intractable cough: It is suitable for cough caused by cold or inhalation of irritating gas, but it is necessary to rescue lung and bronchial lesions.
• 5. Treatment of arrhythmia: During myocardial ischemia, the release of adenosine increases significantly, which can cause angina pectoris, bradycardia, atrioventricular block, etc. After intravenous infusion of adenosine triphosphate, different degrees of atrioventricular block caused by small doses of aminophylline can be eliminated. The occurrence of sick sinus syndrome may also be related to changes in the number of adenosine receptors, increased sensitivity, or abnormally slow breakdown of adenosine.
• 6. Treatment of acute nephritis and hemorrhagic fever with renal syndrome: Aminophylline can inhibit the formation of thrombus and anti-basement membrane antibodies, expand renal blood vessels, increase renal blood flow and filtration rate, improve renal microcirculation, and activate glomerular urinary Function, contribute to the relief of renal failure.
• 7. Treatment of aplastic anemia: Aminophylline can stimulate hematopoietic stem cells, expand bone marrow blood vessels, and is beneficial to granulocyte production.
• 8. Treatment of transplant rejection: Aminophylline is an immunomodulatory drug that can selectively activate suppressive T cells. Inhibit acute rejection in patients with steroid tolerance, reduce serum creatinine, and increase urine output.
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Pharmacological Effects of Aminophylline Powder.

White or light yellow granule or powder. The melting point is 269-274°C. Soluble in water, insoluble in ethanol or ether. Dew in the air and gradually absorb carbon dioxide gas and decompose or theophylline. Slight odor, bitter taste. Use The function and use of this product are the same as that of theophylline. The presence of ethylenediamine in the molecule enhances bronchodilator and coronary vasodilator effects. It is mainly used for bronchial asthma and asthmatic chronic bronchitis, and it can also be used for acute heart insufficiency, cardiac asthma and biliary colic, etc.

Production method of Aminophylline Powder.

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