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Chloropheniramine Maleate is used for allergic rhinitis, cold and sinusitis, and allergic skin diseases such as urticaria, allergic drug eruption or eczema, angioedema, and skin itching caused by insect bites.
Chloropheniramine Maleate Powder is used for colds and allergic diseases of skin and mucous membranes.
Chloropheniramine Maleate Raw Materials can be used to treat urticaria, eczema, dermatitis, drug eruption, pruritus, neurodermatitis, insect bites, and solar dermatitis. It can also be used for allergic dermatitis, Vasomotor rhinitis, drug and food allergies, etc.
Uses and functions of Chloropheniramine Maleate Powder.
Indications: It is used for colds and allergic diseases of skin and mucous membranes. It can be used to treat urticaria, eczema, dermatitis, drug eruption, skin pruritus, neurodermatitis, insect bites, solar dermatitis, and it can also be used for allergic dermatitis and vasomotor rhinitis. , drug and food allergies.
In addition to has a strong competitive effect of blocking the histamine H1 receptor on the target cells of the allergic reaction, and plays an anti-allergic effect by antagonizing the H1 receptor, it also has an anti-M choline receptor effect, so after taking the drug Symptoms such as dry mouth, constipation, thickened sputum, and dry nasal mucosa may occur.
Pharmacological Effects of Chloropheniramine Maleate Powder.
Chlorpheniramine is an H1 receptor antagonist, and its chemical structure belongs to hydrocarbon amines. It can competitively block the histamine H1 receptor on the target cells of the allergic reaction, so that histamine cannot bind to the H1 receptor, thereby inhibiting the allergic reaction caused by it.
But chlorpheniramine does not affect the metabolism of histamine, nor does it prevent the release of histamine in the body.
Chlorpheniramine also has the effect of inhibiting the central nervous system and anticholinergic effect, so there are drowsiness, dry mouth, constipation, thickened sputum and dry nasal mucosa after taking the medicine.
After a long period of clinical practice, it is believed that chlorpheniramine has a strong antihistamine effect, a small dosage, and small side effects. The antihistamine effect of chlorpheniramine is stronger than that of diphenhydramine and promethazine, but the central inhibitory effect is weaker, and the anticholinergic effect is also weaker.
Because of mild adverse reactions such as drowsiness, it is suitable for children and patients who need to work during the day.
Chlorpheniramine still has the effect of reducing tracheal secretion and gastric acid secretion. Before the advent of a new generation of antihistamines, it was the most commonly used antihistamine in clinical practice.
Production method of Chloropheniramine Maleate Powder.
The antihistamine effect of this product exceeds that of diphenhydramine and promethazine, with small dosage and mild side effects.
For urticaria, vasodilation rhinitis, cold, asthma, rhinitis, contact dermatitis, and also for allergies, insect bites and motion sickness caused by drugs and food. Antihistamines.
Like clodrimidone, brompheniramine is also an antihistamine. The production method of brompheniramine is also similar to that of chlortrimidone, except that the starting material is replaced with a bromobenzene compound. It is derived from the salt formation of clotrimidone and maleic acid.
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