Pyridine Hydrochloride Raw Material Powder

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Pyridine Hydrochloride Powder Usage and Synthesis:

Pyridine Hydrochloride Raw Material is the hydrochloride state of pyridine. Pyridine is an organic compound, a six-membered heterocyclic compound containing a nitrogen heteroatom. It can be regarded as a compound substituted by N in the benzene molecule, so it is also called nitrogen benzene, a colorless or slightly yellow liquid with a foul smell. Pyridine and its homologs exist in bone tar, coal tar, gas, shale oil, and petroleum. Pyridine can be used industrially as a denaturant, a dye assistant, and a raw material for the synthesis of a series of products (including pharmaceuticals, disinfectants, dyes, etc.).

Pharmacokinetics of Pyridine Hydrochloride Powder:

Pyridine Hydrochloride Raw Material can be used as organic synthesis intermediate and pharmaceutical intermediate, Pyridine Hydrochloride can be used in laboratory research and development process and chemical pharmaceutical production process, Pyridine Hydrochloride Powder is also one of the raw materials for the production of methyl erythromycin. Chinese name: pyridine, hydrochloride, English name: Pyridine Hydrochloride, Chinese alias: pyridine hydrochloride; pyridine hydrochloride; pyridine hydrochloride, English alias: Pyridinium chloride, CAS number: 628-13-7, molecular formula: C5H6ClN Molecular weight: 115.5608. Raw materials required for the production of Pyridine Hydrochloride Powder: industrial pyridine, chloroform, reagent hydrochloric acid, instruments: four-necked flask, condenser, electric stirrer, dropping funnel, vacuum pump, vacuum oven, oil bath.

Clinical Application of Pyridine Hydrochloride Powder:

As an important pharmaceutical intermediate and fine chemical raw material, pyridine hydrochloride has a wide range of applications and a broad market prospect. In medicine, pyridine hydrochloride as an important pharmaceutical intermediate can be used to synthesize methylerythromycin. Therefore, it has always been the direction of people's efforts to develop a method for preparing pyridine hydrochloride with low cost, high yield and suitable for industrial production. Put a four-neck flask equipped with a reflux condenser, dropping funnel, thermometer and electric stirrer in an oil bath, add 120 mL of hydrochloric acid into the flask, add 90 mL of pyridine into the dropping funnel, start stirring, and turn on the vacuum. Slowly add pyridine dropwise to hydrochloric acid, and control the temperature of the kettle to be less than 60°C. About 0.5h drop finished. Then keep warm at 55°C for 0.5h. At this point, an aqueous solution of pyridine hydrochloride was formed. Heat the above pyridine hydrochloride solution to boiling, stir, and remove dilute hydrochloric acid under a vacuum of 70kPa. When the temperature of the kettle reaches 80 "C, dilute hydrochloric acid is removed, and white PDHC crude product is precipitated in the kettle. Distillation: heat the crude product to 150 °C. Collect 90 "C ~ 110 "C fractions under a vacuum of 3kPa to obtain The finished product is 105g, the melting point is 79.5℃～83.0℃, the yield is 85%, and the content is 97.5%.

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