Plant extract Grifola Frondosa Powder

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Grifola Frondosa Extract Powder Usage and Synthesis.

Ashwagandha Grifolafrondosus, also known as Bay Leaf Polyporus Polyrorusfrondosus, commonly known as Mushroom, known as the "dancing mushrooms" or "dancing mushrooms" in Japan, the taste of its crispy meat, protein content is higher than the mushroom 1/3.

Its flavour is fragrant and crispy, protein content is 1/3 higher than that of shiitake mushroom, the content of essential amino acids is high, and it is rich in vitamins and minerals, which is popular in Japan, Europe and the United States and other countries and regions.

Ashwagandha also has high medicinal value, ashwagandha polysaccharide extracted from ashwagandha is the strongest anti-tumour activity of all fungal bioactive substances, and the vast

majority of fungal polysaccharide preparations orally ineffective, with the exception of ashwagandha polysaccharides, ashwagandha D-complex is the current hot spot of the United States and Japan's research and development.

Uses of Grifola Frondosa Extract.

Ashwagandha extract has the value of improving microcirculation in the body, improving human immunity, promoting fat decomposition, strengthening the body to lose weight, beauty and so on,and can be used for cancer prevention, anticancer, regulating blood pressure, anti-AIDS, preventing anaemia, slowing down the aging process, and enhancing brain and intelligence.

Pharmacological Effect of Grifola Frondosa Extract.

1.Anti-tumour effect of the aqueous extract of Ashwagandha fruiting bodies on mouse sarcoma 180 inhibition rate and on mouse Ehrlich's ascites tumour (carcinoma) inhibition rate of more than 90%;Ashwagandha polysaccharides on the toe inoculation and axillary inoculation of Lewis lung carcinoma inhibition rate of 67.83%. 72.44% and 45.36% ～ 46.31%, respectively, the inhibition rate on the Colon carcinoma were 50.68% ~56.03% and 37.31%~40.47%; Ashwagandha polysaccharide D-fractions showed stronger tumour suppression effects.

By regulating the body's immune function, such as activating the natural killer cells, complement and phagocytosis, so as to achieve the role of cancer prevention and anti-cancer.

2. Immunomodulatory effect of D-fraction of Ashwagandha polysaccharide was activated by natural killer cells, cytotoxic T-cells and delayed sensitisation T-cells by 1.5-2.2 times after 10 days of I.P.

injection (0.5mg/kg) or oral intake (1.0mg/kg) in mice, and the amount of interleukin-1 and superoxide negative ions was also improved, and interleukin-2 was improved by 1.7 times; relevant

studies showed that Related research shows that ashwagandha polysaccharide can stimulate macrophages to accelerate the release of cytokines.

3.Antiviral effect of ashwagandha polysaccharide can inhibit influenza virus, herpes simplex virus type I. Japanese scholars have proved that the dextran sulfate of ashwagandha has the activity of

inhibiting HIV, and it can improve the symptom of Kaposi's sarcoma which is complicated by advanced AIDS patients.Mechanism for ashwagandha polysaccharide to promote the role of interferon induction.

4. Other effects of ashwagandha 500mg/times, twice a day for 6 weeks to hypertensive patients,found to have significant antihypertensive effect. Diabetic rats fed 1g of Ashwagandha seed powder per day showed a reduction in blood glucose, and similar changes in plasma insulin and triglycerides as blood glucose.

Ashwagandha extract significantly reduced the increase in blood glutamine transaminase (SGPT) and blood glutamic oxaloacetic transaminase (SGOT) concentrations due to liver injury caused by oral administration of 4-acetaminophen.

Preparation method of Bulk Grifola Frondosa Extract Powder.

1. Water extract production process will be the original herb chopped, put 400kg of herbs to the extraction tank (6M3), the first time to add 12 times the amount of water, heating reflux for 1 hour.

The second time to add 8 times the amount of water, heating reflux for 1 hour.Extracted by the pipeline filter and then centrifuged by the secondary centrifuge centrifugal liquid,centrifugal liquid concentrated under reduced pressure to a thick paste, add 95% ethanol, filtration,vacuum drying of the precipitate that is obtained.The content of this product is about 20% by phenol sulphuric acid method.

2. alkali extract production process will be the original herb chopped, add 1NaOH solution, 70 ℃ stirring extraction three times, each time 2 hours, the extract is combined, centrifugation, centrifugal liquid, centrifugal liquid concentrated under reduced pressure to a thick paste, add 95% ethanol precipitation, centrifugation, precipitate washed with ethanol, vacuum drying that is obtained.The content of this process product is 16%～18% by phenol sulphuric acid method.

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