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Cistanchis are a group of annual parasitic plants native to North America and East Asia that grow in sandy soils in the United States and northeastern China. They are dug up in the spring while the seedlings are still fresh or just above the ground, and the inflorescences are then excised, sliced, and dried in the sun, where they are called "Sweet Cistanche". Those collected in autumn and soaked in brine are called "salty cistanche"; after the salt is removed, they are sliced and dried in sunlight or steamed with water and wine and dried in air.
Uses and functions of Cistanche Extract.
Cistanchis may exert a testosterone-like effect, promoting sexual desire and ability. Cistanchis stimulate sperm production and semen secretion, promoting libido by filling the seminal vesicles.
Cistanchis also display an overall ability to strengthen the body.
The herb inhibits gonadotropin-like (hormone-like) effects without affecting the normal balance of testosterone in the body. According to traditional Chinese medicine, it acts as an aphrodisiac and has been shown to be used for impotence.
Cistanchis have also shown efficacy against premature ejaculation. Cistanchis may help other herbs to work by helping to regulate the neuroendocrine secretion of the male reproductive system, thus maintaining a normal hormonal balance.
Pharmacological Effect of Cistanche Extract Powder.
1.Effects on the central nervous system on lixiviate mice, it can increase the content of hypothalamic NE, striatal DA and brainstem 5-HT, and can reduce the content of 5-HIAA.
The ethanol extract of Cistanchis given to rats by continuous gavage for 40 days can increase the content of hypothalamus norepinephrine and 5-hydroxyindoleacetic acid, and increase the ratio of norepinephrine to dihydroxybenzeneacetic acid; there is a certain increase of striatal dihydroxybenzeneacetic acid, while there is no significant effect on the limbic brain area monoamine neurotransmitters.
2.Adjustment of endocrine and metabolic effects Cistanchis extract has an adjusting effect on the decrease and increase of nucleic acid content in liver and spleen of animals with yang and yin deficiencies; it has the effect of activating the adrenal gland to release corticosteroid hormone; it can enhance the luteinising function of the hypothalamus-pituitary-ovary, improve the responsiveness of the pituitary to LRH and the luteinising function of the ovary, and enhance the responsiveness of the pituitary to LRH and the ovary to LH without affecting the endocrine balance of natural Endocrine balance of the reproductive cycle; Cistanchis extracts of certain organic acids have the effect of promoting salivary secretion in mice; it can increase the synthesis of DNA in the liver of yang-deficient animals; it can promote the synthesis of RNA; it can improve the metabolism of nucleic acid of protein; its dilute alcoholic leachate is added to the water to feed rats, it can promote the growth and development; it can prolong the lifespan of some animals.
3. The effect on immune function: Infusion of aqueous solution of Cistanchis in mice at 50-100mg per kg can increase the weight of spleen and thymus; increase the phagocytosis rate of macrophage; increase the value of haemolysin and haemolysed vacuoles; increase the content of cAMP and decrease the content of cGMP in abdominal macrophages; increase the rate of conversion of lymphocytes and increase the content of 3H-TdR infiltrated into lymphocytes; enhance the delayed-phase hypersensitivity reaction.
The low concentration of Cistanchis (5mg/mL) increased the Ea node rate of normal human peripheral blood lymphocytes, but had no effect on the Et node rate, while the high concentration (50mg/mL) decreased the Et node rate.
Cistanche reduced the percentage of ANAE+ lymphocytes at high and low concentrations. Administration of 60% Cistanchis decoction 0.5 mL to mice for 8 consecutive days had the effect of enhancing the foot pad response after SRBC attack.
4.Androgen-like effectThe crude extract of Cistanchis has androgen-like effect, which can increase the weight of seminal vesicles prostate and other parasympathetic organs.
Betaine and ergosterol glycosides isolated from Cistanchis have the same androgen-like effect, in which the effect of betaine is stronger than that of crude extract, and it is initially assumed that betaine and ergosterol glycosides are the main active ingredients of Cistanchis androgen-like effect.
Phenylethanol glycosides including ergosterol glycosides isolated from this product also improve sexual function.
Ingredient of Bulk Cistanche Extract Powder.
The main substances extracted and separated from Cistanche are cistanoside A, B, C, H (cistanosideA, B, C, H), ergosterol (acteoside), echinacoside, heptadecane, nineteen, twenty-one, N, N-dimethylglycinemethylester, betaine, daucosterol, β-sitosterol, mannitol, stearic acid and so on.
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