Raw Materials Atractylodes Rhizome Extract Powder

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Atractylodes Rhizome Extract Powder Usage and Synthesis.

Cangzhu Extract is a yellowish-brown oily liquid extracted from the rhizome of Asteraceae plant Cangzhu, the main component is volatile oil, and Cangzhu Alcohol is its main active ingredient. Cangzhu belongs to the Asteraceae plant commonly used thatched cangzhu or northern cangzhu, dried rhizomes into medicine. Warm, sweet and bitter taste, to the liver, spleen and kidney meridians, the main function of drying dampness and spleen, clinically used in the treatment of loss of appetite, abdominal distension and diarrhoea and other digestive disorders.

Uses of Atractylodes Rhizome Extract.

Atractylodes macrocephala strengthens the spleen, dries dampness, relieves depression and expels filth. It is used for treating dampness in the spleen, tiredness and sleepiness, epigastric distension, loss of appetite, vomiting, diarrhoea, dysentery, malaria, phlegm, oedema, seasonal colds, wind-cold and dampness paralysis, impotence of the feet, and night blindness.

1. Sinus tachycardia with Cangzhu injection intramuscular injection treatment of 19 cases, the drug 3 to 8 days back to normal 18 cases, 1 case of improvement.

2. Paediatric diarrhoea atractylodes macrocephala with chenpi, thick park, patchouli, sand nuts, baked licorice (Shenjushan), 84 cases of treatment with soup, 74 cases cured, 6 cases improved.

3. Bacterial dysentery Cangzhu with rhubarb, roasted strawberry, fried almonds, Qiangwu, a total of 1.5g each time, 2 times a day, 96 cases of treatment, 62 cases cured, 28 cases improved, ineffective 6 cases.

4. Streptomycin toxic reaction with Cangzhu tablets or Cangzhu injection to prevent and control streptomycin ototoxicity and perioral numbness, the effect is satisfactory.

5. Burns and scalds with Cangzhu powder and white sesame oil paste on the local.

6. Rickets with compound cohesion method of preparation of Cangzhu volatile oil treatment of 96 cases of patients aged 2 to 3 years old, the symptoms improve the efficiency of 85.4%. Cangzhu syrup for internal use, 2 times a day, each time 5mL treatment, efficacy and vitamin D is similar.

Pharmacological Effect of Atractylodes Rhizome Extract.

1. The role of the central nervous system of the volatile oil of Atractylodes macrocephala has a small amount of frogs have a sedative effect, at the same time make the spinal cord reflex hyperactivity; a large number of inhibitory effect, and ultimately to the respiratory paralysis and death. Cynanchum officinale and its β-eudesmus oil alcohol and anti-electrocution-induced spasm in mice.

2. The role of the cardiovascular system of Atractylodes macrocephala extract small amount of intravenous injection, causing a mild increase in blood pressure in rabbits, a large number of blood pressure; the isolated toad heart has an inhibitory effect on the lower limbs of the toad vasculature has a weak dilatation effect.

3. The effect on blood sugar Cangzhu decoction or alcohol infusion 8g/kg orally or subcutaneously, normal rabbits have a slight tendency to rise in blood glucose; decoction 10g/kg gavage, also get the same result; but the same dose of tetracycline diabetic rabbits, blood glucose is slightly rising that is falling to the level of blood glucose below the filling of the drug before the only difference is not significant; thereafter, in the daily filling of the drug in the 10 days, the blood glucose continues to fall, and the difference is significant; stop 4 days of the drug, and the difference is significant, and the difference is not significant, and the difference is not significant. Thereafter, blood glucose decreased continuously during 10 days of daily dosing, and the difference was significant; blood glucose did not increase to the level before dosing from 4 to 17 days after stopping the drug.

Cangzhuoside on mice, rats, rabbits and dogs have hypoglycaemic effect, at the same time reduce myoglycogen and hepatic glycogen, inhibit gluconeogenesis, so that oxygen consumption is reduced, blood lactate content increased. Its hypoglycaemic effect may be related to its in vivo Pasteur effect, inhibition of intracellular oxidative phosphorylation, interfering with the process of energy transfer.

Pharmacological Effect of Atractylodes Rhizome Extract.

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