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Product details
The mechanism of action of toltrizulil is to interfere with the nuclear division and mitochondria of coccidia, affect the respiratory and metabolic functions of coccidia, and make the endoplasmic reticulum of cells expand and serious vacuolation occur, thus causing the death of coccidia. It mainly acts on the schizogenetic and gametic reproductive stages of coccidia.
Uses of Toltrazuril.
(1) Poultry toltrazuril is mainly used for poultry coccidiosis. This product to chicken type, Brucei, giant, tender, toxic, gentle Eimeria; Eimeria glandulata Turkey: Eimeria Turkey; Eimeria anseris and Eimeria truncata of geese had good inhibitory effect. A dose of 7mg/kg or 25mg/kg concentration of drinking water for 48h, not only effectively prevent coccidiosis, so that coccidiosis oocysts disappear, and does not affect the growth and development of chicks and the production of immunity to coccidiosis.
(2) Giving 20mg/kg or lO ~ l5mg/kg toltrazulide to lambs can effectively prevent and control lamb coccidiosis.
(3) lO ~ 15mg/kg drug feed is very effective for rabbit hepatosphaera and enterosphaera.
(4) Relevant data confirmed that the drug withdrawal period of broilers should be 19 days.
In vitro study of Toltrazuril.
Toltrazuril is an antigenic animal drug that acts on coccidian parasites. Toltrazuril induces changes in the fine structure of coccidia during development, mainly due to swelling of the endoplasmic reticulum and Golgi apparatus and abnormalities in the surrounding nuclear space, which interfere with nuclear division. Toltrazuril causes a decrease in the parasite's respiratory monase.
Product Method of Bulk Toltrazuril Powder.
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