Pharmaceutical Pleuromulin Raw material powder

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Pleuromulin Powder Usage and Synthesis.

Pleurin truncatus is a broad-spectrum diterpene antibiotic produced by Pleurus. It can inhibit the protein synthesis of bacteria, thus achieving the effect of inhibiting bacterial growth. It works in a different way than other types of antibiotics. In the mechanism of action. Truncated pleurotins mainly act on the ribosome level of bacterial cells, and inhibit the synthesis of bacterial proteins by inhibiting the activity of peptidyl transferase, so as to achieve a broad spectrum antibacterial effect. The main skeleton of truncated pleurotins is composed of three rings, and the basic structure of the group is eight membered rings. The carbonyl group on the five-membered ring and the hydroxyl group on C-11 are the necessary groups for activity, and most foreign studies are to chemically modify C-14, so as to greatly improve its antibacterial activity and bioavailability. Because C-14 of the truncated pleurin drugs contains free hydroxyl groups, it is not active; By modifying C-14, the derivatives with enhanced antibacterial activity against bacteria and mycoplasma can be obtained.

Uses of Pleuromulin.

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Pharmacological action of Pleuromulin.

Product Method of Bulk Pleuromulin Powder.

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