Pharmaceuticals Dimenhydrinate Raw Materials powder

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Dimenhydrinate powder Usage and Synthesis.

It is a double salt of diphenhydramine and 8-clofylline. It has the same effect as diphenhydramine hydrochloride, but its antihistamine effect is weaker than the latter. It can inhibit the emetic chemical receptive area of the brain, and has general central inhibition and anticholinergic effects, thus having sedative and antiemetic effects. The absorption is rapid and complete after oral administration, the effect takes 15 to 60 minutes, the effect lasts 3 to 6 hours, the elimination phase half-life (t1/2β) 4-6 hours, and the plasma protein binding rate is high. It is metabolized primarily in the liver and excreted in the urine as metabolites. Patients with liver dysfunction who take this product can produce accumulation in the body and should be reduced.

Drug interaction of Dimenhydrinate powder.

1. Do not drink alcohol after taking the drug, and do not take it with other central nervous depressants.

2. This product can make ethanol, central nervous system inhibitors, tricyclic antidepressants and other synergies. It can briefly affect the absorption of barbiturates and sodium sulfanilate. When used with sodium p-aminosalicylate, the blood concentration of the latter was reduced.

3. Take it with food or milk to reduce the irritation of the stomach.

Pharmacological action of Dimenhydrinate.

Product method of Bulk Dimenhydrinate powder.

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