HRK Supply Tetramethylpyrazine raw Materials powder

Related Attributes

Product details

Tetramethylpyrazine Powder Usage and Synthesis.

Tetramethylpyrazine is a vasodilator that acts on the circulatory system. The main dosage forms are injection, capsules, dropping pills and other dosage forms. It can dilate blood vessels and inhibit platelet aggregation. It is clinically used for the treatment of ischemic cerebrovascular diseases (such as insufficient blood supply to the brain, cerebral thrombosis, cerebral embolism), cardiovascular diseases and other diseases caused by poor blood circulation.

Chronic pulmonary heart disease: ligustrazine can inhibit platelet aggregation, dilate pulmonary blood vessels, reduce whole blood viscosity and red blood cell aggregation index, and has a good effect on improving cardiopulmonary function and alleviating clinical symptoms.

Coronary heart disease: ligustrazine can dilate blood vessels, has a good effect on controlling the attack of angina pectoris and improving myocardial ischemia, and reduces the degree of myocardial cell damage by improving myocardial ischemia.

Insufficient cerebral blood supply: the main symptoms are dizziness, headache, nausea, blood pressure fluctuation, etc. Ligustrazine can act on cerebral blood vessels and reduce the related symptoms caused by insufficient cerebral blood supply by expanding cerebral blood vessels.

Cerebral thrombosis: Ligustrazine can depolymerize aggregated platelets, reduce platelet surface activity, reduce blood viscosity, change blood flow degeneration, and prevent and relieve the formation of cerebral thrombosis.

Pharmacological action of Tetramethylpyrazine.

Ligustrazine is a bioactive ingredient extracted from ligustrum chuanxiong, a widely used traditional Chinese medicine. It can inhibit platelet aggregation, enhance vasodilation, increase cerebral blood flow, and have neuroprotective effects. Ligustrazine injection has been widely used in the treatment of ischemic stroke, coronary heart disease, diabetic nephropathy and knee osteoarthritis in China. Ligustrazine has also been evaluated clinically for the treatment of pressure ulcers, as a salvage agent for patients with non-Hodgkin's lymphoma, and as a treatment for bronchial asthma and vertebrobasilar dysfunction.

Product method of Bulk Tetramethylpyrazine Powder.

Butanedione monooxime was formed by condensation of butanone and ethyl nitrite, and then methylmethylpyrazine was obtained by reduction and cyclization. The cyclic reaction products were distilled by steam, and the distillate was cooled, crystallized and filtered to obtain crude tetramethylpyrazine. Water recrystallization and activated carbon decolorization were used for refining. To prepare its hydrochloride, it can be dripped into acetone with an ethanol solution containing 15%-20% hydrogen chloride to form a salt.

Why choose us?

HRK Factory

About Shipping