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Almotriptan Raw Material Powder
Product Overview:
API Raw Material Almotriptan Raw Material Powder is a migraine treatment,Wholesale high purity Almotriptan Powder from China API Raw Material Supplier-Henrikang,The logistics is fast, the delivery cycle is short, and the customs clearance is easy. Professional export service team.
Almotriptan Raw Material Powder Attributes
Product Name: Almotriptan Raw Material Powder
CAS: 181183-52-8
MF: C21H31N3O7S
Specification: 99% min Almotriptan
Sample: Almotriptan Powder
Keywords: Almotriptan Powder,Almotriptan Raw Material Powder,Almotriptan Powder Supplier
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Almotriptan Raw Material Powder Details
Almotriptan Powder Usage and Synthesis:
Eletriptan is a triptan migraine drug indicated for the acute treatment of migraine with or without aura in adults. Migraine (Migraine) is a common chronic neurovascular disease, manifested by recurrent headaches, autonomic dysfunction, and various combinations of other neurological symptoms. Attacks are often accompanied by numerous autonomic nervous system symptoms, such as nausea, vomiting, pale complexion, rapid heart rate, rapid breathing, and gastrointestinal dysfunction. Premonitory manifestations such as numbness, speech difficulties, numbness in one limb, or hemiparesis, lasting several minutes or half an hour.
Pharmacokinetics of Almotriptan Powder:
Almotriptan Powder is a potent vascular selective 5-HT1B and neuronal 5-HT1D receptor agonist with 6-fold higher affinity for 5-HT1D receptor than sumatriptan (Imigran, Imitrex) and higher affinity for 5-HT1B 3 times higher than sumatriptan. This product also has a high affinity for 5-HT1F receptors. Human 5-HT1B receptor mediates intracranial vasoconstriction. 5-HT1D receptors are mainly located in the presynapse of trigeminal nerve endings.
Clinical Application of Almotriptan Powder:
Almotriptan Powder inhibits neuroinflammation in the dura mater of animals. Therefore, this product may exert anti-migraine effect by constricting intracranial blood vessels and inhibiting neuroinflammation. This product is more lipophilic than sumatriptan and other existing triptans, and can penetrate the blood-brain barrier. Almotriptan Malate (LAS 31416) is a selective serotonin 1B/1D (5-HT1B/1D) receptor agonist indicated for the treatment of migraine attacks in adults.
