Amantadine Raw Material Powder

Product Name: Amantadine Raw Material Powder

CAS: 768-94-5

MF: C10H17N

Specification​: 99% min Amantadine Powder

Sample:  Amantadine Powder

Keywords: Amantadine Raw Material Powder,Amantadine Powder,Amantadine Powder Supplier

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Amantadine Powder Usage and Synthesis:

Amantadine Powder was approved by the U.S. Food and Drug Administration in October 1966 as a preventive drug for influenza and has since been approved for the treatment of influenza virus in adults. Amantadine Powder is an antiviral drug and also an anti-parkinsonian drug. Uses It is used in the manufacture of synthetic adamantane derivatives such as amantadine hydrochloride. Amantadine Powder was discovered in 1969 to reduce the symptoms of Parkinson's disease, a drug-induced extrapyramidal syndrome. The U.S. Food and Drug Administration approved a controlled-release formulation of amantadine for the treatment of dyskinesias in patients with Parkinson's disease in 2017.

Pharmacokinetics of Amantadine Powder:
Amantadine Powder is a weak antagonist of NMDA-type glutamate receptors, which increases the release of dopamine and blocks the reuptake of dopamine, and has anticholinergic effects similar to trihexyphenidyl. This drug may also increase the release of norepinephrine from nerve endings in the brain. It can treat the motor dysfunction of Parkinson's disease, and Amantadine Powder can also improve the dyskinesia after long-term treatment of dopaminergic drugs in Parkinson's disease.

Clinical Application of Amantadine Powder:
Amantadine Powder is used to synthesize adamantane derivatives such as amantadine hydrochloride, etc.; the structural unit of L-piperidinamide catalyst, which can be used in the enantioselective Strecker reaction of phosphonoimine. The effect of amantadine may be weak, and patients with severe symptoms need to be treated with other drugs; amantadine may cause hallucinations and other reactions, especially in patients with mental decline, advanced age, ankylosing, and advanced patients; amantadine is anti-dyskinesia The effect may last less than 1 year;