Betamethasone Raw Materials Powder

CAS:378-44-9

MF: C22H29FO5

MW: 392.47

EINECS: 206-825-4

Specification​: 99% min Betamethasone Powder

Sample: Betamethasone Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Betamethasone Raw Materials Usage and Synthesis.

Betamethasone is a hormone medicine. It is mainly used for anti-inflammatory and anti-allergic purposes. It is suitable for rheumatoid arthritis and various skin diseases. Betamethasone acts like dexamethasone, its anti-inflammatory effect is stronger than dexamethasone, desipramine, hydrocortisone, with fewer side effects.

Betamethasone is used for allergic and autoimmune inflammatory diseases. Now it is mostly used in active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukaemia, etc. It is also used in the comprehensive treatment of certain infections.

Betamethasone Cream is used to relieve symptoms of inflammation and itching occurring in hormone-sensitive dermatoses in children and adults aged 13 years and older.

Betamethasone sodium phosphate injection:

1, This product is used for allergic and autoimmune inflammatory diseases.

2、It is used for active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukaemia.

3、Used in the comprehensive treatment of certain infections.

Uses and functions of Betamethasone Raw Materials Powder.

Betamethasone is the isomer of dexamethasone, the role and use of dexamethasone acetate, its sodium, water retention effect and dose are smaller than the latter. Glucose metabolism and anti-inflammatory effect is stronger than hydrocortisone, 15 times as much as hydrocortisone, but the sodium retention effect is more than 100 times as much as that of hydrocortisone, in primary hypoadrenocorticism, it can be used for replacement therapy with glucocorticosteroids. It is also indicated in low renin low aldosterone syndrome and postural hypotension due to phytoneuropathy. Because this product is easy to cause oedema, mostly for external topical application for the treatment of seborrheic eczema, contact dermatitis, anus, pubic itching and other conditions. Mainly used for allergic and autoimmune inflammatory diseases. Now mostly used for active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukaemia, etc., also used for the comprehensive treatment of certain infections.

Pharmacological Betamethasone Powder.

Glucocorticoid drugs. With a variety of pharmacological effects such as anti-inflammatory, anti-allergic and immune suppression, the clinical application is very wide.

1, anti-inflammatory effect: glucocorticoids reduce and prevent the tissue response to inflammation, thereby reducing the manifestation of inflammation.

2, immunosuppressive effect: prevent or inhibit cell-mediated immune response, delayed allergic reaction, reduce the number of T lymphocytes, monocytes eosinophils, reduce the binding capacity of immunoglobulin and cell surface receptors, and inhibit the synthesis and release of interleukin, thus reducing the transformation of T cells to lymphoblastoid cells and reducing the expansion of primary immune response.

3、Anti-toxicity, anti-shock effect: glucocorticoids can counteract the stimulation reaction of bacterial endotoxin to the organism, reduce cellular damage, and play the role of protecting the organism.

Production method of Betamethasone Raw Powder.

Betamethasone acetate is converted to betamethasone by treatment with hydrochloric acid in a methanol-chloroform-water mixture according to U.S. Patent 3164618.