Paracetamol Piroxicam Raw Materials Powder

CAS:36322-90-4

MF: C15H13N3O4S

MW: 331.35

EINECS:252-974-3

Specification​: 99% min Piroxicam Powder

Sample: Piroxicam Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Piroxicam is a non-steroidal anti-inflammatory drug.

Piroxicam is used for the relief of localised pain such as muscle pain, joint pain and pain and swelling caused by strains, sprains and sports injuries; symptomatic treatment of osteoarthritis.

Piroxicam medical insurance types are: piroxicam tablets, piroxicam capsules for medical insurance category B, piroxicam injection, piroxicam gel, piroxicam ointment, piroxicam application, piroxicam patch for non-medical insurance.

Uses and functions of Piroxicam.

A non-steroidal anti-inflammatory drug with antipyretic, analgesic and anti-inflammatory properties.

Its action The mechanism of action may be due to the fact that it inhibits the biosynthesis of prostaglandins, the mediators of inflammation, rather than producing anti-inflammatory effects by stimulating the pituitary-adrenal axis.

The drug is indicated for rheumatoid arthritis, osteoarthritis, ankylosing excitatory spondylitis, acute musculoskeletal injuries and acute gout.Used in the treatment of rheumatic and rheumatoid arthritis, there are more obvious analgesic, anti-inflammatory and certain anti-clock effect, its role is slightly stronger than indomethacin.

A strong non-steroidal anti-inflammatory analgesic, can also be used in the treatment of rheumatic and rheumatoid arthritis, has obvious analgesic, anti-inflammatory and a certain degree of swelling effect.

Pharmacological Effects of Piroxicam.

Piroxicam is a long-acting non-steroidal anti-inflammatory, analgesic and antipyretic drug with analgesic, anti-inflammatory and antipyretic effects.

Piroxicam exerts its pharmacological effects by inhibiting cyclooxygenase, causing a reduction in local prostaglandin synthesis in tissues and inhibiting leukocyte chemotaxis and lysosomal enzyme release.

Oral absorption is rapid and complete, food can reduce the rate of absorption, but does not affect the total amount of absorption.Tmax3~5h.T1/2 is 30~86h, PPB is more than 90%, T1/2 is prolonged in patients with renal insufficiency, and it is mainly metabolised by the liver.

Due to the longer T1/2, a single administration can maintain a relatively stable blood concentration for 24h, and multiple administrations can easily lead to accumulation. The effective blood concentration is 1.5~2μg/ml.

Stable blood concentration can be reached 7-12d after the start of treatment. 66% of the drug is excreted from the kidney,33% from the faeces, and <5% of the drug is in its original form.

Production method of Piroxicam Raw Powder.

0.5t of 2-aminopyridine is consumed per tonne of Inflamenco.