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Lornoxicam Powder Raw Material
Product Overview:
Lornoxicam has strong antipyretic, analgesic and anti-inflammatory effects. China factory export Lornoxicam Powder Raw Material, supply high quality Lornoxicam powder raw material at factory price. Best Lornoxicam Powder Supplier and manufacturer from China.
Lornoxicam Powder Raw Material Attributes
Product Name: Lornoxicam Powder Raw Material
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Specification: 99% min Lornoxicam Powder Raw Material
Test Method: HPLC
CAS: 70374-39-9
MF: C13H10ClN3O4S2
Sample: Lornoxicam Powder Raw Material
Keywords: Lornoxicam Powder, Lornoxicam Powder Supplier, Lornoxicam Powder Raw Material
Lornoxicam Powder Raw Material Details
Lornoxicam Powder Description:
Lornoxicam has strong antipyretic, analgesic and anti-inflammatory effects. China factory export Lornoxicam Powder Raw Material, supply high quality Lornoxicam powder raw material at factory price. Best Lornoxicam Powder Supplier and manufacturer from China.
Lornoxicam Powder is a non-steroidal anti-inflammatory analgesic, and Lornoxicam Powder Raw Material is a non-steroidal anti-inflammatory analgesic, which is a thiazide derivative and has strong antipyretic, analgesic and anti-inflammatory effects . Lornoxicam Powder Raw Material relatively balancedly inhibits the activity of the two isomers of cyclooxygenase (COX), thereby inhibiting the biosynthesis of prostaglandins and producing anti-inflammatory and analgesic effects.The COX1:COX2 inhibition ratio of this drug is 0.6, so it has good analgesic effect of traditional NSAID. At the same time, the drug does not inhibit the activity of 5-lipoxygenase, so it does not inhibit the synthesis of leukotrienes, nor does it shunt arachidonic acid to the 5-lipid oxidase pathway, while arachidonic acid and 5-lipid oxidase The metabolites of lipoxygenase can inhibit the impulse process of nociceptors in the spinal cord, so that lornoxicam exerts an analgesic effect similar to that of opioid peptide analgesics. Both lornoxicam and naproxen can significantly reduce the rest pain score, joint tenderness index and joint swelling index in patients with OA, and there is no significant difference between the two drugs, but lornoxicam is better than Naproxen. In vivo safety studies in animals have shown that the toxicity profile is consistent with half-oxidase inhibition. The digestive tract and kidneys are the most sensitive organs to toxic effects. Animal test results show that lornoxicam for injection has no vascular irritation and muscle irritation, and will not cause allergy and hemolysis.
Lornoxicam Powder Uses:
Lornoxicam is commonly used in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gouty arthritis and hysteritis. It is also suitable for acute pain after surgery, moderate to severe pain caused by trauma, neuralgia (such as acute sciatica), low back pain and advanced cancer pain. Tenoxicam has anti-inflammatory, analgesic and antipyretic effects, and can also inhibit platelet aggregation. It is as effective as piroxicam, lornoxicam, indomethacin and diclofenac in standard animal inflammation models, and stronger than aspirin, mefenamic acid and naproxen. Like other NSAIDs, it is also an inhibitor of prostaglandin synthesis. It may produce anti-inflammatory effects by scavenging active oxygen free radicals or inhibiting their production, and inhibiting leukocyte chemotaxis and phagocytosis. 】Mainly used for rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis, extra-articular diseases such as tendonitis, strain and sprain, acute gout, etc. Non-steroidal anti-inflammatory analgesics. Inhibits prostaglandin synthesis by blocking cyclooxygenase, but has no effect on ester oxygenase.