HRK Supply Minocycline raw Powder Minocycline

CAS:10118-90-8

MF:C23H27N3O7

MW:457.48

EINECS:800-277-5

Specification: 99% min Minocycline Powder

Sample:Minocycline Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Minocycline powder Usage and Synthesis.

1. Minocycline can be used to treat urinary tract, gastrointestinal tract, respiratory tract and gynecological infections caused by other tetracycline resistant strains, as well as pyoderma, osteomyelitis and ear, nose and throat infections, and is also used in the treatment of falciparum malaria.

2, in addition, minocycline is also suitable for staphylococcus, streptococcus, pneumococcus, Neisseria gonorrhoeae, dysentery bacillus, Escherichia coli, Klebsiella, Proteus, Pseudomonas aerosa, treponema pallidum and chlamydia and other pathogens sensitive to this product caused by the following infections: 1. Sepsis, bacteremia. 2. Superficial suppurative infection: folliculitis, pyoderma, tonsillitis, perishoulder, dacryocystitis, gingivitis, vulvitis, trauma infection, post-operative infection, etc. 3. Deep suppurative diseases: mastitis, lymphatic (nodal) inflammation, submandibular gland inflammation, osteomyelitis, osteitis. 4. Acute and chronic bronchitis, asthmatic bronchitis, bronchiectasis, bronchopneumonia, bacterial pneumonia, heteropneumonia, pulmonary sepsis. 5. Dysentery, enteritis, infectious food poisoning, cholangitis, cholecystitis. 6. Peritonitis. 7. Pyelonephritis, pyelocystitis, urethritis, cystitis, prostatitis, epididymitis, intrauterine infection, gonorrhea. 8. Otitis media, paranasal sinusitis, submandibular gland. 9. Syphilis.

Uses of Minocycline.

Minocycline is mainly used for rickettsial disease, mycoplasma pneumonia, lymphogranuloma, malnutrition, plague, cholera, brucellosis (combined with streptomycin) and so on. It can also be applied to systemic or local infections caused by sensitive strains of E. coli, aerogenes, Shigella, Haemophilus influenzae, Klebsiella, etc.

In addition, for gonococcal, syphilis and spirochetes, Listeria, Clostridium, anthrax, actinomyces, and clostridium infections, when patients are not resistant to penicillin, this product (or other tetracyclines) can be considered. It may also be considered for infections caused by sensitive strains of streptococcus. As for Staphylococcus aureus, most strains are resistant to this class of drugs. In addition, the product can also be used in the adjuvant treatment of amebiasis.

Similar to tetracycline or doxycycline, it is mainly used for sexually transmitted diseases caused by seat sores, rosacea, gonorrhea and chlamydia trachomatis. Although it has certain curative effect on urinary, respiratory and soft tissue infections, meningococcal carriers, otitis media and sinusitis caused by some drug-resistant bacteria, its clinical application is greatly limited due to its many adverse reactions.

Drug interaction of Bulk Minocycline powder.

1. Since minocycline can reduce prothrombin activity, the dosage of anticoagulants should be reduced when it is combined with anticoagulants.

2. Since acid-making drugs (such as sodium bicarbonate) can reduce the absorption and activity of this product, this product and acid-making drugs should be avoided at the same time.

3. When it is combined with drugs containing aluminum, calcium, magnesium and iron ions, insoluble complexes can be formed to reduce the absorption of this product.

4. When cholestyramine or colestipol are used together with this product, the absorption of this product may be affected.

5. Since barbiturates, phenytoin or carbamazepine can induce the activity of microsomal enzymes and reduce the blood concentration of this product, the dose of this product should be adjusted when used.

6. The combination of the general anesthetic methoxyflurane and this product can cause fatal renal toxicity.

7. Because minocycline can interfere with the bactericidal activity of penicillin, it should be avoided in combination with penicillins.

8. The combination of this product with strong diuretics (such as furosemide, etc.) can aggravate kidney damage.

9. The combination of this product with other hepatotoxic drugs (such as anti-tumor chemotherapy drugs) can aggravate liver damage.

10. Combined with oral contraceptives, this product can reduce the effect of oral contraceptives.

Product Methods of Minocycline.