Esculin Raw Materials powder Esculin

CAS:531-75-9

MF:C15H16O9

MW:340.28

EINECS:208-517-5

Specification​: 99% min Esculin powder

Sample:Esculin powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Esculin Powder Usage and Synthesis.

Firstly, ‌ aesculoetin has anti-inflammatory and ‌ analgesic effects. ‌ The results showed that ‌ erythroetin had inhibitory effects on conjunctivitis, ‌ dextran, ‌ 5-hydroxytryptamine and histamine arthritis, and ‌ inhibitory intensity was 35, 28, 20, 8%, respectively. ‌ In addition, ‌ has a weak analgesic effect and ‌ has an inhibitory effect on formaldehyde-induced "arthritis", although ‌ has a weaker effect. ‌

​Azaletin also affects urine output and uric acid excretion. ‌ all kinds of administration routes can improve the excretion of uric acid in rats and rabbits, ‌ has no diuretic effect on normal rats, ‌ has significant diuretic effect on mice. ‌ In addition, ‌ azaletin has antibacterial, ‌ anticoagulant and inhibiting aldose reductase in rat lens.

Use of Esculin.

Aesculotin has anti-inflammatory, antibacterial, anticoagulant, analgesic and other activities, and has significant diuretic effect on mice. Aldose reductase can inhibit the lens of the rat eye, is a growth inhibitor of Bacillus subtilis, and has an inhibitory effect on chemical to cancer.

It's a bitters. Naringin dihydrochalcone obtained by hydrolyzing and hydrogenation of this product is a sweetener, and the sweetness is about 150 times that of sucrose.

It has anti-inflammatory, antibacterial, anticoagulant, analgesic and other activities, and has significant diuretic effect on mice. Aldose reductase can inhibit the lens of the rat eye, is a growth inhibitor of Bacillus subtilis, and has an inhibitory effect on chemical to cancer.

Pharmacological Effect of Esculin.

1. Anti-inflammatory and analgesic: intraperitoneal injection of 10mg/kg in rats showed inhibitory effects on the "arthritis" of cyclothyrageenan, dextroliver, 5-hydroxytryptamine and histamine, with inhibitory intensity of 35,28,20,8%, respectively. It has also been reported that it also has an inhibitory effect on formaldehyde-induced "arthritis", but the effect is weaker than diagonal-induced "arthritis "; The inhibition of dextran "arthritis" was also not significant. It inhibited the formation of granuloma in rats (cotton ball method), the erythema reaction caused by ultraviolet irradiation on the back of guinea pigs, and the increase of capillary permeability caused by histamine. It has a weak analgesic effect.

2. Influence on urine volume and uric acid excretion: all kinds of administration routes can enhance the excretion of uric acid in rats and rabbits, and have no diuretic effect on normal rats, but have significant diuretic effect on mice.

3. Others: It has antibacterial, anticoagulant and inhibiting aldose reductase in rat eye lens.

Product Method of Bulk Esculin Powder.