Raw Materials Podophyllum Resin Powder

CAS:9000-55-9

MF:C88H92O34

MW:1693.65168

EINECS:232-546-2

Specification​: 99% min Podophyllum Resin Powder

Sample:Podophyllum Resin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Podophyllum Resin Usage and Synthesis.

Onychomycosis resin can be used for the treatment of various viral warts, such as condyloma acuminatum, common warts, flat warts, plantar warts, but also used for skin cancer and limited keratosis pilaris.

Onychomycetin, a substance extracted from the plant Onychomycetes, is cytotoxic and is used in the treatment of a number of cancers such as Hodgkin's and non-Hodgkin's lymphomas and childhood lymphoblastic leukaemia.

Onyxin, the main component of onychomycetin, inhibits the herpes virus and is used in the treatment of viral sexually transmitted diseases. Side effects, such as gastrointestinal reactions and bone marrow suppression, need to be noted when using onychomycetin.

The dosage of onychomycetin needs to follow the doctor's instructions, usually by intravenous injection, each time 1-3mg per kg of body weight, twice a week, can be administered for 2-3 months.

Uses of Podophyllum Resin.

Onychocarpine is a substance extracted from the plant Onychocarpus in the family Onychocarpaceae, and its main component is onychocarpine. Onychocarpus resin has a variety of effects and functions.

Firstly, it can regulate menstruation and activate blood circulation, promote birth, and induce stillbirth, and has a certain therapeutic effect on gynaecological diseases.

Secondly, colchicine-like action of onychomycetin is "cytotoxic" and has inhibitory effects on a variety of tumour models, including acute leukaemia, metastatic lymphoma, localised lymphoma, adenoma and melanoma. In addition, it has inhibitory effects on human KB cells.

Onychomycetin also blocked late S- or G-phase cells, possibly through the binding of onychomycetin thiophene glycan to topoisomerase-II.

Additionally, onychotoxin effectively inhibits herpesviruses and inhibits mitosis in the mid-cell phase for viral sexually transmitted diseases. It should be noted that the roots of onychocarpus are bitter, spicy and warm, with a small toxicity, and should be used with caution.

Pharmacological Effect of Podophyllum Resin.

Onychocereus is a commonly used herbal medicine with a variety of pharmacological effects. The crystalline constituents proposed from the aniseed lotus have an excitatory effect on the isolated frog heart, stopping in a contracted state.

It has a dilating effect on the ear vessels of rabbits; it has a mild constricting effect on the hind limb vessels of frogs, the small intestine of rabbits and the renal vessels. Onychocercin is the main component of onychocercin, with anticancer effect, anti-herpes simplex virus and immunosuppression, anti-fertility and other effects, but more toxic.

Ashwagandha ethoside is a lignocellulosidic active ingredient isolated from onychomycetin, which is a cell cycle-specific antitumour drug, acting in the late S-phase or G2-phase, and its site of action is topoisomerase Ⅱ, which forms a kind of stable cleavage complex between drug-enzyme-DNA, interfering with the DNA topoisomerase Ⅱ, resulting in the failure to repair the damaged DNA.

Ghostwort fat can also be used to clear away heat and detoxification, phlegm dispersal, dispel blood stasis and reduce swelling and other effects, commonly used in carbuncles, boils, scrofula, sore throat, bruises, snake bites and other diseases.

It should be noted that the onyx has a certain degree of toxicity, the use of should be strictly in accordance with the instructions of the doctor or pharmacist.

Drug interactions of Bulk Podophyllum Resin Powder.