Raw Materials Loquat Leaves Extract powder

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Specification: 99% min Loquat Leaves Extract Powder

Sample:Loquat Leaves Extract Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Loquat Leaves Extract Powder Usage and Synthesis.

1. Chronic bronchitis with loquat leaves 90g, eggplant stem 150g, add water decoction into 2000mL, plus simple syrup 240mL, 3 times a day, 10mL each time, the treatment of 167 cases, the recent control of 42 cases, 60 cases of apparent effect, 35 cases of improvement, ineffective 30 cases, the total effective rate of 82.0%.

2. Long-term cough mute, sputum with blood loquat leaf punch, each 10g (equivalent to 36g of raw medicines), 2 times a day internal service, the effect is better.

Uses of Loquat Leaves Extract.

Loquat Leaf Extract is a natural medicine extracted from the leaves of the loquat tree, which contains a variety of components with medicinal value, such as ursolic acid, flavonoids and carotenoids.

Loquat leaf extract has a variety of effects and actions, such as hypoglycaemic, immunomodulatory, hypothermic, local stimulant and cardiotonic effects.

Studies have shown that loquat leaf extract can be used for the prevention and control of diabetes, where flavonoids and carotenoids have hypoglycaemic effects.

In addition, loquat leaf extract can also play an immunomodulatory role by regulating the immune system in terms of non-specific immunity, humoral immunity and cellular immunity.

Ursolic acid in loquat leaf extract also has a stabilising and cooling effect, while the camphor in it is a topical chiropractic agent with local stimulant and cardiotonic effects. In addition, the bitter amygdalin in loquat leaf extract also has a certain analgesic effect.

Pharmacological Effect of Loquat Leaves Extract.

1. Anti-tumour effect polyphenols have cytotoxic effects on human oral tumours. Intraperitoneal injection of ursolic acid extracted from loquat leaves at 10 and 20mg/(kg-d) significantly prolonged the survival period of S180 mice from 13.2d to 20.0 and 28.7d in the control group, and intraperitoneal injection of 5, 10 and 20mg/(kg-d) reduced the weight of tumour from 5.52g to 3.01g, 2.25 and 1.78g, and the inhibition rate was 45.5%, 59.2% and 67.8%, respectively. The tumour weight was reduced from 5.52g to 3.01, 2.25 and 1.78g in the control group, and the tumour inhibition rates were 45.5%, 59.2% and 67.8% respectively.

When the concentration of ursolic acid was 5 and 10 μmol/L, the number of S180 cells was significantly reduced, which indicated that the reduction of tumour weight was due to the toxic effect of ursolic acid on S180 cells.

2.Antibacterial effectsEthyl acetate extract and ethanol extract of loquat leaves had inhibitory effects on Staphylococcus aureus, Staphylococcus albus, Streptococcus haemolyticus, Pneumococcus pneumoniae, and Cattacoccus.

Oleanolic acid has different degrees of bacteriostatic effect on Staphylococcus aureus, hemolytic streptococcus, Escherichia coli, Fusarium dysentery bacillus, typhoid fever bacillus, Salmonella cholera in swine and so on.

3. The effect on the respiratory system of amygdalin by gastric acid or amygdalin enzyme decomposition into hydrocyanic acid and benzaldehyde, after absorption, inhibit cytochrome oxidase, inhibit the oxidative metabolism of the body of the common carotid artery reflexively deepen the respiration, the respiratory centre is sedative, so that respiratory movement tends to be quiet and to achieve the effect of suppressing cough and asthma.

The decoction of loquat leaves and its ethyl acetate extract have asthma and expectorant effects. Saponins have the effect of causing bronchial mucous membrane secretion, internal use has the effect of expectorant. Caffeic acid has the effect of cough expectorant.

4. Hypoglycemic effect from the loquat leaf methanol extract of triterpenoids and sesquiterpene compounds isolated from diabetic mice have significant hypoglycemic effect, its mechanism of action may be to stimulate the pancreatic B-cells, increase the level of insulin release, so as to achieve the effect of lowering blood glucose.

Extraction Processes of Bulk Loquat Leaves Extract Powder.

The crushed loquat leaves were extracted by refluxing with ethanol to obtain an extract in the form of an infusion, the ethanol was recovered, and the above extract was washed with water sufficiently and dried to obtain a dry extract, which was dissolved with ethanol and decoloured, and the decolourised solution was precipitated by adding water to precipitate a large number of precipitates by recovering ethanol, adjusting the pH to 2-2.5, separating and collecting precipitates, and washing them with water to neutrality, and drying them in vacuum, to obtain crude extracts with the main constituent being Ursolic Acid.