Raw Materials Aucklandia Lappa Extract Powder

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Specification: 99% min Aucklandia Lappa Extract Powder

Sample:Aucklandia Lappa Extract Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Aucklandia Lappa Extract Powder Usage and Synthesis.

Mullein is a Chinese herb rich in volatile oils, sesquiterpenes, lactones, and other components that have a variety of pharmacological effects.

Mullein extract is obtained by extracting the active ingredients in Mullein and has various effects such as anti-inflammatory, anti-tumour, antibacterial and blood pressure lowering.

Studies have shown that Mullein extract contains components that lower blood cholesterol and triacylglycerol levels, as well as components that dilate blood vessels and lower blood pressure.

In addition, dehydrocostus lactone in wood sorrel extract has significant anti-tumour activity, promoting apoptosis and cell cycle arrest. Mullein extract can also promote the secretion of growth inhibitors in the stomach and intestinal peristalsis.

In conclusion, Mullein extract has a variety of pharmacological effects, but should be used in accordance with medical advice, pay attention to the dose and indications!

Uses of Aucklandia Lappa Extract.

Firstly, the main anti-inflammatory components in Mullein are sesquiterpenes, which also have lysosomal membrane stabilising and antiproliferative effects, and dehydromullein lactone, the main component of sesquiterpene lactones in Mullein, has significant antitumour activity.

Secondly, the effects of Mullein on the cardiovascular system are mainly manifested in lowering blood pressure and anti-blood coagulation, and Mullein extract contains components that lower blood cholesterol and triacylglycerol levels, as well as vasodilating and antihypertensive components.

In addition, the volatile oil, dehydrocostus lactone, and hydrocarbon-lactone components of Mullein have inhibitory effects on ADP-induced platelet aggregation. Mucuna pruriens also showed bacteriostatic effects against Helicobacter pylori and significant inhibitory activity against the cariogenic effects of Streptococcus mutans.

Traditionally, Mullein has had utility in the treatment of oral diseases such as halitosis, dental caries and periodontitis

Pharmacological Effect of Aucklandia Lappa Extract.

1.Inhibition of platelet aggregation

Experiments show that the wood incense in a certain concentration range of rabbit platelet aggregation performance has obvious inhibitory effect on the aggregated platelets have a significant function of promoting depolymerisation, the intensity of the effect is proportional to the dose of the drug.

The volatile oil of Mullein was ineffective, and its active ingredient was in the water-soluble part. In addition, the inhibitory effect of platelet aggregation of Mucuna pruriens is 2.12 times stronger than that of Astragalus membranaceus, and the inhibition of platelet aggregation and depolymerisation function of both of them is stronger than that of the single drug, indicating synergistic effect.

5. Antibacterial effect

The decoction has a slight inhibitory effect on S. paratyphi in the test tube, but not on dysentery bacillus, Pseudomonas aeruginosa, Staphylococcus, Streptococcus, and 10 kinds of fungi, such as Xylococcus and its Mongolian varieties.

Volatile oil 1:3000 concentration can inhibit the growth of streptococcus, staphylococcus aureus and white staphylococcus, the role of Escherichia coli and diphtheria bacillus is weak.

6. Hypoglycaemic effect

The ethanol extract of Yunmu Xiang was given to mice orally on the 3rd day of administration, blood glucose began to decline, and on the 7th day to a minimum of (156.57±4.35) mg/%. In the same experiment, the hepatic glucose content showed biphasic changes with an initial upward trend as compared to the control values followed by a continuous decline.

However, this effect was not due to increased secretory action of insulin, but was the result of the action of different secretory glands on glucose metabolism.

7. Anti-tumour effect

Mullein with Buddha's hand, Augustus za composed of a compound on the growth of mice tumours (S180, Lewis lung cancer) inhibitory effect. And can inhibit the metastasis of Lewis lung cancer in mice.

The anti-tumour effect is achieved by improving the hypercoagulable state of the body and improving the immune function of the body.

Extraction Methods of  Bulk Aucklandia Lappa Extract Powder.

CO2 supercritical extraction method Mullein powder → CO2 supercritical fluid extraction for 2 hours → Mullein volatile oil Note: Supercritical CO2 fluid extraction operated at higher pressure and lower temperature is favourable for the extraction of the volatile oil of Mullein and the active ingredient dehydrocostus lactone in it.

The suitable operating conditions are 1500-2000kPa, 25℃-35℃. 

The volatile oil was extracted by steam distillation method by crushing Mullein and using the volatile oil extractor in accordance with the Chinese Pharmacopoeia under the volatile oil determination method, and the volatile oil was obtained after drying with anhydrous sodium sulfate, and the yield was 1.5%.

The volatile oil is light yellow transparent oily liquid with special strong fragrance.