Raw Materials Alisma Orientalis Extract Powder

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Specification: 99% min Alisma Orientalis Extract Powder

Sample:Alisma Orientalis Extract powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Alisma Orientalis Extract Powder Usage and Synthesis.

Zelda extract is the active ingredient extracted from the Zelda plant and has a variety of pharmacological effects.

Firstly, zelda extract has obvious cholesterol-lowering and anti-atherosclerotic effects, which can reduce serum total cholesterol and triglycerides, increase the HDL content and the ratio of HDL cholesterol to total cholesterol, which is conducive to the prevention and treatment of atherosclerosis.

Secondly, zelda extract also has anti-fatty liver effect, which can reduce the liver fat content of fed bile and high-fat rabbits.

In addition, the extract of zelda has an effect on the cardiovascular system, with a slight antihypertensive effect about half an hour after intravenous administration to dogs and rabbits.

At the same time, the extract of zedoary also has the effect of anti-platelet aggregation, anti-thrombosis and enhancement of fibrinolytic enzyme activity, which can inhibit or reduce the occurrence and development of atherosclerosis from the aspects of lowering blood lipids, inhibiting the damage of endothelial cells, and anti-thrombosis. However, long-term administration of large doses of aqueous extract of zelda may lead to chronic nephrotoxicity.

Therefore, the use of extracts of zeylanol should be used in moderation and under the guidance of a physician.

Uses and functions of Alisma Orientalis Extract.

First of all, the extract of zedoary can diuresis, seepage of dampness, drainage of heat, pass the lymphatic turbidity, for oedema, urinary frequency, urinary urgency, urinary pain and other symptoms have a relieving effect.

Secondly, it is able to reduce blood lipids, and has a preventive and therapeutic effect on diseases such as hypercholesterolaemia and atherosclerosis.

In addition, the extract of zedoary has the effects of anti-platelet aggregation, anti-thrombosis and enhancement of fibrinolytic enzyme activity, which can prevent the occurrence of thrombotic diseases.

In conclusion, senna extract is a kind of herbal extract with various medicinal values, which has a certain effect on the prevention and treatment of various diseases.

Pharmacological Effect of Alisma Orientalis Extract.

1. Hypolipidemic effect

The extracts, alcoholic extracts and alcoholic extracts of Zea mays have preventive and curative effects on experimental hyperlipidaemia in rabbits. Zelda can reduce various lipids in the aorta, especially cholesterol significantly, which leads to the reduction of aortic plaques.

The fat-soluble part of zelda is injected intraperitoneally, and has the effect of clarifying plasma lipids on rats with hyperlipidaemia caused by oral administration of cotton seed oil; it has obvious cholesterol-lowering and anti-atherosclerotic effects on experimental animals with hypercholesterolaemia.

Its active ingredient is Alisol A and A, B, C acetate, especially Alisol A acetate has the strongest effect.

Alisol A can inhibit the absorption of cholesterol in the small intestine of rats, inhibit the ability of small intestine esterification of cholesterol in mice.

2. Liver protection and anti-fatty liver effects of senna extract can make feeding cholesterol and high-fat rabbit liver fat content decreased, the extract contains choline, lecithin, amino acids and benzene - acetone soluble part of the T have anti-fatty liver effects, carbon tetrachloride caused by acute liver injury has a protective effect, can inhibit the accumulation of intrahepatic fat, inhibit the decline of plasma and hepatic phospholipids and improve the function of hepatic pigment excretion.

2. Hepatoprotective and anti-fatty liver effects

Alisol extract can reduce the fat content in the liver of rabbits fed with cholesterol and high fat, and the choline, lecithin, amino acid and benzene-propanone soluble part T contained in the extract has the effect of anti-fatty liver, and it has the protective effect on the acute hepatic injury induced by carbon tetrachloride, and it can inhibit the accumulation of fat in the liver, and it can inhibit the decline of plasma and hepatic phospholipids, and it can improve hepatic excretion function of pigment.

Zelda can significantly reduce total cholesterol, cholesteryl ester, triglyceride and total ester content in the liver of experimental high-fat animal models.

Diarrhoea can reduce the Lee index of experimental obese rats uterus and testis around the fat index and serum triglyceride content, its mechanism of action may be related to cholesterol metabolism and inhibition of cholesterol enzymes and triglyceride synthesis in the liver due to.

3.Diuretic effect

Zedoaria extract has diuretic effect on human and animals, which can increase the excretion of sodium, chloride, potassium and urea in urine. Intraperitoneal injection of the fluid infusion of senna can reduce nitroglycerin-induced nephritis in rabbits blood urea and cholesterol retention.

Diarrhoea contains up to 147.5 mg% of potassium and significantly increased urinary potassium excretion in adrenalectomised rats. The ethanol extract of Zeloda had a dose-dependent inhibition of renal Na+, K+-ATPase activity.

Extraction method of Bulk Alisma Orientalis Extract Powder.

1. Firstly, crush Zeloda into 16 mesh fine powder, take 500g, add 65% ethanol 1000mL ultrasonic extraction for 4 times, the extract will be decompression, recovery of ethanol and concentrated to thick paste;

Then the thick paste in turn with petroleum ether, ethyl acetate, 80% ethanol and water extraction, respectively, petroleum ether-soluble, ethyl acetate-soluble, alcohol-soluble and water-soluble 4 parts of the extract, each part of the solvent will be recycled into a thick paste, that is, obtained.

2. 200g of Zelda drinking tablets ground into powder, soaked in petroleum ether to remove impurities, filtering the coarse powder shade dry. Water extract preparation method is: take 100g diarrhoea crude powder decoction 3 times, will collect the filtrate to 2000r-min-1 centrifugation 10min, stand for 1d, take the supernatant, distilled and concentrated to 50mL, to become a 2g-mL-1 solution of the drug.

Alcoholic extract was prepared as follows: take 100g of the crude powder of senna and add 600mL of 75% ethanol, rotary evaporator evaporation 3 times, filtration, take the filtrate, centrifuged at 2000r-min-1 for 10min, go to the precipitate, the supernatant will be distilled and concentrated to make 2g-mL-1 raw drug solution.

3. the dried tuberous roots of zeolian powder, through the 250μm sieve, mixed uniformly and accurately weighed 5.0g, placed in a 50mL mill conical flask, add 25mL 95% ethanol ultrasonic extraction 2 times, each time for 30min. extracts were combined, centrifuged and separated, take the supernatant, the ethanol extract.