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HRK Supply Skin whitening Tetrahydrocurcumin raw Powder

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Product Overview:

Tetrahydrocurcumin (THC), as the active and main metabolite of curcumin produced in organisms, is hydrogenated from the curcumin isolated from the rhizome of curcumin in the ginger family.
Tetrahydrocurcumin is the main whitening active ingredient in natural turmeric root extract, which not only has the strongest tyrosinase inhibitory activity, but also has excellent chemical stability, and the appearance of odorless white powder, thus overcoming the chemical instability of ordinary turmeric extract easy to stain the skin. Ordinary turmeric extract is yellow, poor chemical stability, with photosensitivity, in the light, easy to react with the skin and make the skin stain

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HRK Supply Skin whitening Tetrahydrocurcumin raw Powder Attributes

Tetrahydrocurcumin Raw Materials Powder

CAS:36062-04-1

MF:C21H24O6

MW:372.41

EINECS:609-201-3

Specification: 99% min Tetrahydrocurcumin Powder

Sample:Tetrahydrocurcumin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:light yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

HRK Supply Skin whitening Tetrahydrocurcumin raw Powder Details

Tetrahydrocurcumin powder Usage and Synthesis.

The whitening effect of tetrahydrocurcumin is better than that of arbutin because of its strong activity of inhibiting tyrosinase. It can effectively inhibit the generation of oxygen free radicals and remove the formed free radicals, and has obvious antioxidant effects, such as anti-aging of human skin, repair, fade pigment, freckle and so on. This product is widely used in whitening, freckle removal, antioxidant skin care products, such as cream, lotion and essence products.

It is used as new pharmaceutical raw materials and intermediates because of its antioxidant, anti-tumor and anti-atherogenic effects. Use as a food additive is another new function of this product.

Uses of Tetrahydrocurcumin.

Tetrahydrocurcumin is a natural functional whitening material with strong tyrosinase inhibiting activity, and its whitening effect is better than that of arbutin, which is known to us. It can effectively inhibit the generation of oxygen free radicals and remove the formed free radicals. It has obvious anti-oxidation, inhibition of melanin, repair and freckle removal, anti-inflammatory activity, blocking inflammatory process and so on. In addition, the inhibition of free radicals, lipoxy and enzymes of various inflammatory factors, collagenase, and hyaluronidase reflects the potential anti-aging effect of tetrahydrocurcumin.

Tetrahydrocurcumin

In vitro study of Bulk Tetrahydrocurcumin powder.

Tetrahydrocurcumin (THC) has a number of attractive properties not shared with Curcumin that may make it superior. Tetrahydrocurcumin inhibited lipoxygenase as low as 1 μM. Tetrahydrocurcumin is tested for its ability to inhibit CYP2C9, CYP3A4, CYP1A2 and CYP2D6. Tetrahydrocurcumin yields dose-dependent inhibition of CYP2C9, and to a lesser extent, CYP3A4. Tetrahydrocurcumin exhibits maximum inhibition of CYP2C9 and CYP3A4 at 50 to 100 μM. Tetrahydrocurcumin does not show a consistent dose-response inhibition of CYP1A2 or CYP2D6 over the range of concentrations tested. In some cases, the percent inhibition exceeds 100%. The effect of Tetrahydrocurcumin on cancer cell viability is measured. Sup-T1 cells, T-cell lymphoblastic lymphoma cells, are treated with Tetrahydrocurcumin to determine its ability to induce growth inhibition using an MTS assay, and the corresponding IC50 values are in the mid-to-high micromolar range.

Tetrahydrocurcumin raw