Prostaglandin E2 Raw Materials powder Prostaglandin E2

CAS:363-24-6

MF:C35H38ClN5O5S

MW:676.23

EINECS:245-855-2

Specification​: 99% min Prostaglandin E2 powder

Sample:Prostaglandin E2 powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Prostaglandin E2 Powder Usage and Synthesis.

Dinoprostol is a kind of prostaglandin, which has contractile effect on the uterus in all stages of pregnancy, especially the uterus in the third trimester. The drug can directly act on the smooth muscle of the uterus and stimulate the smooth muscle of the uterus to produce uterine contractions similar to full-term labor. It can also directly soften the cervix, which is conducive to cervical dilation. Dinoprostol can also cause gastrointestinal smooth muscle contraction, and can also act on vascular smooth muscle.

Use of Prostaglandin E2.

One of the most biologically active prostaglandins that induces cervical maturation and labor, mediates bradykinin-induced vasodilation, and regulates adenylate cyclase. Tumor cells overexpressing cyclocooxygenase-2 were more aggressive, angiogenic, and apoptosis-resistant, which may be due to PGE2-induced angiogenic factor expression and stabilization of anti-apoptotic protein survivin. PGE2 has a mixed effect on the immune system. It inhibits T cell activation in vitro, indicating that it is an immunosuppressant. However, in vivo, it affects the expansion of the Th17 subgroup and the differentiation of the Th1 subgroup of T helper cells, suggesting that it acts as an immune activator.

Uterine stimulants. It is used for pregnancy oxytocin, induction of labor in the second trimester, therapeutic abortion and preoperative cervical dilation. A few cases may have chills, vomiting, mild diarrhea, generally in a short time can be self-alleviated, or easy to control after symptomatic treatment. Intravenous drip has similar symptoms of venous inflammation, which disappears spontaneously after withdrawal. The uterine contractions should be closely observed and the dosage should be adjusted at any time to prevent uterine contractions from being too strong and uterine rupture.

Pharmacological Effect of Prostaglandin E2.

Product Method of Bulk Prostaglandin E2 Powder.