Etravirine Raw Material Etravirine Powder

CAS: 269055-15-4

MF: C26H44O4

MW: 435.28

EINECS: 682-331-6

Specification​: 99% min Etravirine

Sample: Etravirine Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Etravirine Raw Materials Usage and Synthesis

Factory Supply Purity 99% Etravirine Raw Material, High Quality Supply Etravirine Raw Powder Factory Supply Supply Etravirine Powder, Manufacturer of Supply Etravirine Raw Materials. Etravirine Powder is a non-nucleoside reverse transcriptase inhibitor (NNRTI), a drug used to treat HIV.

Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV.

Uses and functions of Etravirine Powder

Etravirine (TMC125), is highly potent against wild-type HIV-1, with an EC50 of 1.4 nM to 4.8 nM, and also exhibits some activity against HIV-2, with an EC50 of 3.5 μM.TMC125 also inhibits a range of HIV-1 M subunits and circulating recombinant forms, as well as O viruses.

Pharmacological Effects of Etravirine Raw Powder

Etravirine has a high genetic barrier to resistance development.

In the phase IIb trial, among multiple-treatment patients, including those infected with NNRTIs-resistant and protease inhibitor (PIs)-resistant viruses, TMC125 was active against existing NNRTIs-resistant HIV and was similarly tolerated to controls.

Production method of Raw Etravirine Powder