Nutritional Supplements Vitamin B2 Powder

CAS:83-88-5

MF:C17H20N4O6

MW:376.36

EINECS:201-507-1    

Specification: 99% min Vitamin B2 Powder

Sample:Vitamin B2 Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Yellow to orange

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Vitamin B2 Powder Usage and Synthesis.

Vitamin B2 helps to prevent and control iron deficiency anaemia, but also has a certain antihypertensive effect, in the clinic is mainly used to prevent and control vitamin B2 deficiency caused by xerostomia, lingual inflammation, dry and cracked lips, conjunctivitis, scrotal inflammation, and seborrheic dermatitis, etc.

Uses and functions of Vitamin B2.

Used in the treatment of riboflavin deficiency, conjunctivitis, nutritional ulcers, systemic nutritional disorders and other diseases.

Riboflavin exists in green vegetables, soybeans, rice, wheat, yeast, liver, heart and dairy, riboflavin in the body is distributed in the tissues, constituting a coenzyme in the body in the system of hydrogenation of the complementary hydrogenation, participate in redox reactions, play a role in the transmission of hydrogen atoms.

When riboflavin deficiency, it will affect the biological oxidation, so that the metabolism is impaired, resulting in lesions occurring in the mouth, eyes, external genitalia, such as stomatitis, labyrinthitis, conjunctivitis, scrotal inflammation and so on.

Riboflavin is mainly used as medicine, food additives and feed additives, in the medicinal aspect, used for multivitamin or vitamin B2 preparations, but also used as sugar-coated tablets and capsules of yellow colouring agent.

When used as food additives, on the one hand, it has the effect of strengthening nutrition, on the other hand, it is also used as a yellow colouring agent. The LD50 for intraperitoneal injection in rats is 560mg/kg.

Vitamin B2 is a vitamin that promotes the growth and development of the organism and plays an important role in the metabolic process of the human body. When deficient, it is easy to suffer from conjunctivitis, keratitis, lingual inflammation and so on.

It can be used in table salt at 100~150mg/kg, in solid drinks at 10~13mg/kg, in baby food at 4~8mg/kg, in cereal and its products at 3.0~5.0mg/kg, and in drinking liquid and milk drink at 1~2mg/kg, and can also be used as yellow colouring agent.

Functionality of Vitamin B2.

Vitamin B2 (riboflavin) is a water-soluble vitamin that is easily digested and absorbed, and the amount excreted increases or decreases according to the body's needs and possibly the degree of protein loss; it does not accumulate in the body, so from time to time it has to be replenished with food or nutritional supplements. Unlike vitamin B1, vitamin B2 is resistant to heat, acid and oxidation.

Clinically vitamin B2 tablets are used for the prevention and treatment of vitamin B2 deficiency, such as keratitis, dry and cracked lips, lingual inflammation, scrotal inflammation, conjunctivitis, seborrheic dermatitis, etc.; they are also used for the treatment of malnutrition, progressive weight loss and other diseases caused by total gastro-intestinal extra-nutritional and insufficient intake.

Product method of  Bulk Vitamin B2 Powder.

Vitamin B2 is naturally found in animal liver, kidney, meat and dairy foods, etc. It is produced industrially by fermentation and chemical synthesis methods.

Fermentation

Take glucose, corn syrup, inorganic salt, etc. as the culture medium, and use special active bacterium, Pseudocystis aristolochiae (Eremotheciumashbyii), to cultivate the deep fermentation at 28℃ for 9d, and the fermentation liquid contains about 6~8g/L riboflavin products. The extraction yield is 60% to 70%.

Synthesis method

The better synthesis method is firstly condensed by 3,4-dimethylaniline and D-ribose at Ph=4 and 28～30℃, then reduced by nickel-catalysed hydrogenation to obtain ribonamide, then coupled with aniline diazonium salt at 16～26℃, then reduced by sodium hyposulphite (insurance powder), and finally cyclosynthesized to vitamin B2 with barbituric acid (tetraoxymethylpyrimidine) in acetic acid.