CAS:  125-46-2

MF: C18H16O7

MW: 344.32

EINECS: 204-740-7

Specification​: 99% min Usnic Acid powder

Packaging: 1kg/bag. 25kg/bag

Brand: Ausreson

MOQ:1KG

Appearance: Bright yellow to yellowish-green fine crystalline powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Last updated: March 2026

What is Usnic Acid? (The Lichen-Derived Bioactive)

Usnic Acid is a unique dibenzofuran derivative found exclusively in lichens. Unlike many botanical extracts, our Usnic Acid Powder is purified to 98% min, ensuring a high-potency crystalline structure that is:

• Naturally Antibacterial: Highly effective against Gram-positive bacteria, including S. aureus and P. acnes.

• Anti-Inflammatory: Supports the body’s natural healing response by modulating inflammatory pathways.

• UV Absorbent: Offers secondary photoprotective benefits in topical applications.

Click here to contact us for more information

Uses and functions of Usnic Acid Powder

Usnic Acid Powder (lichen) are a class of biological organisms with a high degree of genetic stability, also known as lichen-type fungi, which are formed by symbiotic bacteria (ascomycetes or sporangia) and symbiotic algae (cyanobacteria or green algae) through a long period of biological evolution and symbiosis.

Usnic Acid Powder are an important class of organisms in natural ecosystems and are widely found in nature, including plateaus, grasslands, forests, arid deserts, rocky surfaces, and even equatorial and bipolar regions.

Mechanism of Action

• The primary antibacterial mechanism of usnic acid involves inhibiting the mitochondrial respiratory chain and glycolysis processes in microorganisms.
• It effectively suppresses the activity of key enzymes such as acetyl-CoA dehydrogenase and succinate reductase.
• This action disrupts energy (ATP) synthesis, leading to microbial death by energy depletion.
• This unique mechanism also means microorganisms are less likely to develop resistance to it.

Bioactive pharmacological effects of Usnic Acid Raw Powder

1. Antibacterial effect: Pinellic acid can effectively inhibit the growth of Gram-positive bacteria such as Staphylococcus aureus, MRSA, Acinetobacter, Corynebacterium, and can inhibit the growth of Mycobacterium bovis, directly kill the cells of Staphylococcus aureus, and impede the Pseudomonas aeruginosa signaling pathway, suggesting that Pinellia extracts and Pinellic acid can be used for the treatment of acne, rosacea, seborrhoeic dermatitis, and other related dermatological disorders; in addition, it has an eliminating effect on sa-resistant plasmid. In addition, Pinus sylvestris acid has an elimination effect on SA drug-resistant plasmid, the elimination rate is 52% in 24h, and the elimination rate is up to 14.6% in 48h, which may be used for clinical treatment of drug-resistant SA infections.Премиальный порошковый экстракт уснеи (усниновая кислота 98%) - Ausreson

2. Antiviral effect: Studies have proved that pineolic acid has the potential activity of inhibiting the proliferation of rat polyomavirus, which is mainly through the inhibition of the formation of messenger RNA, thus indirectly inhibiting the replication of DNA. Pinus sylvestris has inhibitory activity against Epstein-barrvirus (EBV), with (+)-pinus sylvestris showing the highest inhibitory activity (ED501.0 μg/mL) and (-)-pinus sylvestris showing weaker inhibitory activity (ED505.0 μg/mL).

Production method of Usnic Acid Powder

Usnic Acid Powder is a broad-spectrum antimicrobial agent with powerful inhibitory effect on most Gram-positive bacteria, the concentration of 50μg/mL can completely inhibit bacterial growth, and is used as a highly effective preservative in cosmetics.

It has selective inhibitory effect on streptococcus, the main bacteria causing oral diseases and dental caries. Pinusolidic acid is effective in many skin diseases such as burns, infections, psoriasis and so on.

While Usnic Acid is a powerful natural compound, responsible use is paramount.

• Dosage: Always adhere to manufacturer guidelines or professional advice. Typical usage levels in formulations are low due to its high potency.

• Topical Use: Generally well-tolerated, but a patch test is recommended for sensitive skin.

• Oral Supplementation: Consult with a healthcare professional before starting any new dietary supplement, especially if you are pregnant, nursing, taking medication, or have pre-existing health conditions.

• Regulatory Status: In the USA, it is recognized as a dietary ingredient. Ensure compliance with local regulations (FDA, Health Canada, EFSA guidelines).

Frequently Asked Questions.

No, Usnic Acid is practically insoluble in water. It is soluble in oils (like MCT oil), alcohol, and certain organic solvents. For water-based formulas, we recommend using a propanediol-based delivery system or a specialized solubilizer.

In typical cosmetic formulations, the usage rate ranges from 0.1% to 0.5%. Even at low concentrations, it exhibits significant antibacterial activity.

Each batch undergoes HPLC (High-Performance Liquid Chromatography) testing to guarantee a purity of $\ge 98\%$. We provide a full Certificate of Analysis (COA) and MSDS with every shipment.

Yes. We prioritize eco-friendly extraction methods from renewable lichen sources, ensuring our product meets the "Sustainability" criteria valued by Northern European retailers.

Our Strengths

We possess extensive experience, handling every step from sourcing each ingredient in the formulation to post-filling inspection, all at the most competitive prices and with the fastest delivery times.

InterlGroup owns factory, Main Product Foods additives, Nutritional supplements, Healthcare Products(capsules,Softgels,tablets,Gummies,Liquid Drops,Gum,solid beverage and other customized products), plant extracts.

Support OEM&ODM service，Design label packaging, Overseas in stock, Fast customization, Drop Shipping.

Intergroup is supplying OEM service for the Well-known brands Reson and Ausreson. 

Alibaba International Station No.1 supplier,  Alibaba International Station Number 1, Alibaba International Station Number one.

Поставщик порошка (+)-усниновой кислоты 98% чистоты
Fournisseur de poudre d'acide usnique (+) pure à 98%
Lieferant von (+)-Usninsäure-Pulver mit 98% Reinheit
Proveedor de polvo de ácido úsnico (+) al 98% de pureza
Fornecedor de pó de ácido úsnico (+) com 98% de pureza