Chondroitin Sulfate Raw Materials Chondroitin Sulfate Powder

CAS:4940-11-8

MF:C7H8O3

MW:140.14

EINECS:225-582-5

Specification: 99% min Chondroitin Sulfate Powder

Sample:Chondroitin Sulfate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Chondroitin Sulfate Powder Usage and Synthesis.

Chondroitin sulfate is widely found in human and animal cartilage tissue.

Its medicinal preparation mainly contains chondroitin sulphate A and chondroitin sulphate C isomers, the content of chondroitin sulphate in the cartilage of different species and ages of animals is different.

Its pharmacological effects are as follows: chondroitin sulphate can remove lipids and lipoproteins from the blood, remove cholesterol from blood vessels around the heart, prevent and control atherosclerosis, and increase the conversion rate of lipids and fatty acids in the cells.

Uses and functions of Chondroitin Sulfate.

1. Chondroitin sulphate has been used as a health food or health care drug for a long time in the prevention and treatment of coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases, with no obvious toxic side effects, and it can significantly reduce the morbidity and mortality rate of patients with coronary heart disease. Long-term clinical application found in the arteries and veins wall deposits of fat and other lipids can be effectively removed or reduced, can significantly reduce plasma cholesterol, thus preventing the formation of atherosclerosis.

2. Chondroitin sulphate is used in the treatment of neuralgia, neurogenic migraine, arthralgia, arthritis and scapular joint pain, pain after abdominal surgery.

3. It is effective in preventing and treating the hearing disorder caused by streptozotocin as well as the hearing difficulty and tinnitus caused by various noises.

4. It has auxiliary therapeutic effect on chronic nephritis, chronic hepatitis, keratitis and corneal ulcer, etc. 5. In recent years, it has been reported that chondroitin in shark cartilage has anti-tumour effect. In addition, chondroitin sulfate is also used in cosmetics and wound healing agents.

6. Chondroitin sulphate is also used in eye drops.

Pharmacological Effect of Chondroitin Sulfate.

Chondroitin sulphate is widely found in human and animal cartilage tissues. Its medicinal preparation mainly contains chondroitin sulphate A and chondroitin sulphate C two isomers, the content of chondroitin sulphate in the cartilage of animals of different species and ages is different. Its pharmacological effects are shown as:

1, chondroitin sulfate can remove lipids and lipoproteins in the blood of the body, remove cholesterol from the blood vessels around the heart, prevent and control atherosclerosis, and increase the conversion rate of lipids and fatty acids in the cells.

2, chondroitin sulfate can effectively prevent and control coronary heart disease. For experimental atherosclerosis model with anti-atherosclerosis and anti-atherogenic plaque formation; increase atherosclerosis coronary artery staging or collateral circulation, and can accelerate experimental coronary atherosclerosis or embolism caused by myocardial necrosis or degeneration of healing, regeneration and repair.

3, can increase the cellular messenger ribonucleic acid (mRNA) and deoxyribonucleic acid (DNA) biosynthesis as well as has the effect of promoting cell metabolism.

4, low anticoagulant activity. Chondroitin sulfate has a mild anticoagulant effect, each lmg of chondroitin sulfate A is equivalent to 0.45U heparin anticoagulant activity. This anticoagulant activity does not depend on antithrombin III and play a role, it can play an anticoagulant activity through the fibrinogen system.

5, chondroitin sulfate also has anti-inflammatory, accelerate wound healing and anti-tumour effects.

Product Method of Bulk Chondroitin Sulfate Powder.

Porcine larynx and nasal cartilage were extracted with 2% sodium hydroxide, and the extract was hydrolysed with crude trypsin at 50°C to remove protein and other impurities. Filtration, enzyme hydrolysate adjust pH to 6, add ethanol to make ethanol concentration of 75%. Centrifugation to get the precipitate, that is, chondroitin sulfate crude product. The finished product was obtained by multi-step refining. For pig throat, nasal cartilage, the total yield of 5%.