Thiamine chloride Vitamin B1 HCl Powder Manufacturer

CAS:59-43-8

MF:C12H17ClN4OS

MW:300.81

EINECS:200-425-3

Specification​: 99% min Thiamine chloride Powder

Sample: Thiamine chloride Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: White powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

What is thiamine chloride powder?

Tymamine chloride is a stable, water-soluble form of vitamin B1. In the body, it is converted into an active coenzyme form (thiamine pyrophosphate), which directly participates in energy metabolism, nervous system function, and heart health.

Compared to the commonly available thiamine hydrochloride, thiamine chloride has a slightly different chemical structure, but its bioavailability is equally high. Due to its high purity and stability, it is particularly suitable for powder formulations and functional food additives.

Thiamine chloride Powder Usage and Synthesis.

Vitamin B1 is one of the B vitamins, mainly used for the prevention and treatment of vitamin B1 deficiency and its caused by pediculosis or Wernickes' encephalopathy, also used for peripheral neuritis, myocarditis, dyspepsia, congestive heart failure and other adjuvant therapy; used for vitamin B1 supplementation: including burns, fever, long term chronic infections patients; malabsorption syndrome with liver and biliary system disorders (e.g. alcoholism with Cirrhosis), small intestinal diseases (such as celiac disease, persistent diarrhea, etc.), gastrectomy, hyperthyroidism and hemodialysis patients; malnutrition caused by prolonged parenteral nutrition or insufficient intake, heavy laborers, as well as pregnant women, lactating women.

Usage Recommendations and Precautions

Recommended Dosage:

The daily maintenance dose for adults in Europe and America is typically 1.1-1.2 mg/day, but as a supplement, the common dosage range is 50-100 mg/day. The powder form allows for dosage adjustments to individual needs—it is recommended to use a precision milligram scale for measurement. First-time users should start with a lower dose or consult a healthcare provider.

How to Integrate into Daily Life

• Morning Energy Drink: Mix the measured powder with orange juice (vitamin C may enhance absorption) or a green smoothie.
• Pre-Workout Supplement: Add to water or an electrolyte drink 30 minutes before training.
• Functional Food Preparation: Add to homemade energy bars or nutrition balls.

Safety and Interactions

• Thyamine is a water-soluble vitamin; excess amounts are excreted in urine, making it highly safe.
• A very small number of people may be sensitive; it is recommended to try a small dose first.
• May interact with other medications (such as diuretics); those taking prescription medications long-term should consult a doctor.

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Uses of Thiamine chloride.

Vitamin B1 maintains normal nerve and myocardial function. There is evidence that patients with congestive heart failure often have vitamin B1 deficiencies as a result of diuretic use.

A small, double-blind study found that intravenous vitamin B1 given to patients with congestive heart failure improved their cardiac function. Similar results were found in another earlier study without a control group.Vitamin B1 powder for energy UK

Vitamin B1 can also be supplemented Vitamin B1 will be helpful for people who drink alcohol, have Crohn's disease, are anorexic, or have multiple sclerosis, and it can be used as part of systemic nutritional support.Best Thiamine powder for nootropics

Vitamin B1 can also be used as a treatment for epilepsy, ulcer pain and muscle fiber pain, but of course this needs to be confirmed with further studies.

Pharmacological effect of Thiamine chloride.

In vivo, it combines with ATP to form pyrophosphate of B1, which plays an important role in the decarboxylation reaction of α-keto acid in sugar metabolism, changing pyruvate to acetate, and through the tricarboxylic acid cycle, forming an important connection between glycolysis and oxidative metabolism, promoting carbohydrate metabolism.

When the lack of vitamin B1, pyruvate decarboxylation oxidation is blocked, resulting in the accumulation of intracellular pyruvate, lactate, so that the small arteries dilate, diastolic blood pressure decreases, myocardial metabolism is dysfunctional, and in severe cases, there are circulatory disorders that lead to cardiac insufficiency, generalized edema and so on.

Impaired glucose metabolism, reducing the body's energy supply, so that the normal nerve involvement, sensory abnormalities, vision loss, muscle aches and pains and other symptoms of peripheral neuritis. In addition, vitamin B1 can inhibit the vitality of cholinesterase, and when it is lacking, cholinesterase activity increases, acetylcholine hydrolysis is accelerated, resulting in nerve impulse conduction disorders, affecting gastrointestinal and cardiac function.

Mainly absorbed through the gastrointestinal tract, distributed in all tissues T1/2 for 0.35 hours, metabolized in the liver, excreted through the kidney, normal people daily absorption of vitamin B1 is 5 to 15mg.

Product Method of Bulk Thiamine chloride Powder.

Thiamine hydrochloride is usually obtained by condensation, hydrolysis, neutralization, oxidation and acidification of an excess of acetamidine hydrochloride with α-dimethoxy β-methoxypropionitrile.

Frequently Asked Questions

Q1: What is the difference between thiamine chloride powder and regular vitamin B1 tablets?

A: Powder form offers dosage flexibility, faster absorption potential (no disintegration required), and formulation freedom. It does not contain fillers or binders commonly found in tablets, making it suitable for those sensitive to additives or requiring customized high doses.

Q2: How to determine the quality of thiamine chloride powder?

A: Check if the product provides a third-party laboratory Certificate of Analysis (CoA) to confirm purity (usually >98%), heavy metal residue compliance with USP/EP standards, and whether the production facility is GMP certified.

Q3: Which European and American dietary groups are suitable for?

A: Particularly suitable for active individuals, the elderly, those with dietary restrictions (such as low-carb, vegetarian), drinkers, and those concerned about neurological health. However, pregnant women, breastfeeding women, or those with specific health conditions should consult a doctor before use.

Q4: How to store to maintain efficacy?

A: Store in a cool, dry place, protected from light and sealed. High temperatures, humidity, or direct sunlight may reduce stability. High-quality products typically have a shelf life of 24-36 months under proper conditions.

Q5: Can it be used with other supplements?

A: Yes, thiamine often works synergistically with other B vitamins (such as B complex) to support overall energy metabolism. Supplementing with magnesium may provide additional support for the nervous system. However, if taking high doses of other medications, it is recommended to take them 1-2 hours apart.

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