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Vitamin B1 Thiamine Raw material powder Thiamine hydrochloride
Product Overview:
Thiamine hydrochloride (VitaminB1, VB1), also known as thiamine, is the earliest water-soluble vitamin to be purified by people, chemically known as chlorinated 3-[(4-amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium hydrochloride, which has the effect of maintaining normal glucose metabolism, and is commonly used clinically to prevent and control foot fungus caused by the lack of VB1, and also used for adjunctive treatment of neuritis, dyspepsia and other conditions.
Vitamin B1 Thiamine Raw material powder Thiamine hydrochloride Attributes
CAS:67-03-8
MF:C12H17N4OS.ClH.Cl
MW:337.27
EINECS:200-641-8
Specification: 99% min Vitamin B1 Thiamine powder
Sample:Vitamin B1 Thiamine powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Vitamin B1 Thiamine Raw material powder Thiamine hydrochloride Details
Vitamin B1 Thiamine powder Usage and Synthesis.
Thiamine Hydrochloride is a form of Vitamin B1,USES: Nutritional supplement. Vitamin B1 is involved in the intermediate metabolism of sugars in the body. Insufficient vitamin B1 in the organism, coenzyme carboxylase activity decreases, sugar metabolism is blocked, thus affecting the entire body metabolic process.
Which acetone decarboxylation is blocked, can not enter the tricarboxylic acid cycle Chemicalbook ring, do not continue to oxidation, in the tissue accumulation. At this time, the nerve tissue supply is insufficient, so the corresponding neuromuscular symptoms can appear, such as polyneuritis, muscle atrophy and edema, and in severe cases can also affect the function of the heart muscle and brain tissue. Vitamin B1 deficiency can also cause indigestion, loss of appetite and constipation.
Uses of Vitamin B1 Thiamine powder.
Vitamin B1 plays an important role in maintaining normal nerve conduction, the heart, and the normal activity of the digestive system. When lacking, it is easy to suffer from foot fungus or polyneuritis and other diseases.
China's regulations can be used in infant food, the use of 4 ~ 8mg / kg; in cereals and their products in the use of 3.0 ~ 5.0mg / kg; in the drinking liquid, milk beverages, the use of 1 ~ 2mg / kg. This product can be used to thiamine nitrate fortification, the specific dosage shall be converted.
Biochemical studies, fluorescence and phosphorescence photometric analysis of phosphorus, clinical drugs belong to the vitamin B family, used in the prevention of foot fungus, polyneuritis, central nervous system damage and other conditions of the treatment.
Preparation of Vitamin B1 Thiamine powder.
Product method of Bulk Vitamin B1 Thiamine powder.
Vitamin B1 occurs naturally in foods such as rice bran, bran, lean meats, and peanut rice, and the pure form is usually prepared by chemical synthesis.
Excess acetamidine hydrochloride is condensed with α-dimethoxy-β-methoxypropionitrile in an alkaline (methanol and sodium methanol) medium to 3,6-dimethyl-1,2-dihydro-2,4,5,7-tetraazanaphthalene, which is then hydrolyzed at 98-100°C, then ring-opened to form 2-methyl-4-amino-5-aminomethylpyrimidine in alkaline conditions; this is followed by carbon disulfide and ammonia, and then condensed with acetic-γ- Chloro-γ-acetylpropyl ester, then hydrolyzed and cyclized to thiosulfanilamide hydrochloride in hydrochloric acid at 75-78℃, and finally thiamine hydrochloride was obtained by neutralization with ammonia, oxidation with hydrogen peroxide and acidification with hydrochloric acid.