Nicotinic acid Raw Materials Powder CAS:59-67-6

CAS:59-67-6

MF:C6H5NO2

MW:123.11

EINECS:200-441-0

Specification: 99% min Nicotinic acid Powder

Sample:Nicotinic acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Nicotinic acid Powder Usage and Synthesis.

Constitutes nicotinamide adenine dinucleotide (Coenzyme I, NAD+ or CoI) and nicotinamide adenine dinucleotide phosphate (Coenzyme 11, NADP+ or CoII) Nicotinamide binds to adenine, ribose, and phosphoric acid in vivo to constitute nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, which act as electron carriers or hydrogen transporters in biological redox reactions that depend on molecular structure Nicotinamide part.

The nicotinamide pyridine ring has reversible hydrogen- and electron-addition and dehydrodegeneration properties, transferring hydrogen and electrons during enzymatic reactions. Glucose Tolerance Factor (GTF) is a complex of trivalent chromium, niacin, and glutathione, which is an insulin cofactor that increases glucose utilization and promotes the conversion of glucose to fat.

Niacin reduces blood cholesterol, triglyceride and beta-lipoprotein concentrations and dilates blood vessels.

Uses of Nicotinic acid.

Nicotinic acid is an important chemical additive and corrosion inhibitor, and can be used as antioxidant and anti-gray mist agent in photographic materials. In electroplating, nicotinic acid is also an excellent bright additive, as long as the addition of 1-10g of nicotinic acid per liter of electroplating solution will have a significant effect.

Nicotinic acid is used as antioxidant and anti-graying agent in photographic materials. Will be 0.1% of nicotinic acid aqueous solution added to the photographic emulsion, can increase the stability of the photographic material on the light; in each milliliter of the photographic emulsion to add 5-20mL 0.1% of nicotinic acid aqueous solution, can reduce the gray haze of the photographic material.

Niacin belongs to the vitamin B family and is involved in lipid metabolism, oxidative process and anaerobic decomposition process in human body. Niacin can be generated by the body's tryptophan conversion, the human body is generally not easy to occur niacin deficiency, but when the staple food does not contain niacin, or staple food in the decomposition of niacin, easy to trigger due to the lack of niacin caused by coarse skin disease.

For this reason, niacin is widely used in pasta processing, dairy products and cornmeal preparation. Adding a certain amount of niacin to food can effectively prevent the occurrence of this type of deficiency.

Characteristic of Bulk Nicotinic acid Powder.

White crystal or crystalline powder, odorless or slightly foul odor, slightly acidic taste. Melting point 234-237℃. Freely soluble in hot water, hot ethanol, alkaline water, propylene glycol and chloroform, slightly soluble in water and ethanol, soluble in 1.6g in 100mL water at room temperature, insoluble in ether and ester solvents. 1% aqueous solution PH is 3.0-4.0. stable to heat, acid and alkali. Oral LD505-7g/kg in rats, ADI value is not specified (ECC, 1990).

Product Methods of Nicotinic acid.

It is obtained from 3-methylpyridine by oxidation and acidification. Another method using 3-methylpyridine as raw material is gas phase oxidation with ammonia. Using a fluidized bed reactor, 3-methylpyridine, air and ammonia are mixed proportionally and reacted at 290-360 under the action of vanadium catalyst. The fumonitrile obtained was hydrolyzed with sodium hydroxide at 160°C.

If the hydrolysis is carried out with ammonia, the solubility of the hydrolysis is controlled to obtain nicotinic acid or nicotinamide, respectively. Nicotinic acid can also be produced from nicotine (tobacco). Fluidized bed reactor is used, with ferric ammonium citrate as the catalyst, with air at 65-105 ℃ gas phase oxidation. Nicotinic acid can also be produced industrially from quinoline, which is commonly oxidized and decarboxylated by ozone or oxidized and decarboxylated by nitric acid.