Yohimbine Raw Material Yohimbine Powder

CAS: 146-48-5

MF: C21H26N2O3

MW: 354.44

EINECS: 205-672-0

Specification​: 99% min Yohimbine 

Sample: Yohimbine Powder

Packaging: 1kg/bag. 25kg/bag

Brand: Henrikang

Appearance: Brown Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

China Yohimbine Raw Material Factory Supply Yohimbine Raw Material, High Quality Yohimbine Powder Purity 99% Yohimbine Raw Powder, Yohimbine extract Powder comes from the dried bark of Yohimbine. Low content brownish red powder, white to creamy white fine powder with a slightly bitter taste.

Manufactory Supply Yohimbine  Raw Material, High Purity Yohimbine Powder, High Quality Yohimbine Raw Powder.

Uses and functions of Yohimbine Powder

Yohimbine selectively blocks presynaptic α2 receptors and promotes the release of norepinephrine. It causes the cavernous nerve endings to release more norepinephrine, reduces penile venous return, and facilitates engorged erection. When applied in small amounts, it can cause swelling of the perineum, stimulate the spinal erectile centre and cause hypersexual function. Yohimbine Hydrochloride can also produce psychological excitation effect and increase sexual desire.

• ① When applied in small quantities, it acts on the erectile centre of the lumbar spine and induces hypersexual function. ② It has adrenergic blocking effect. Clinical application: Trial for functional impotence due to neurasthenia, also used for secondary impotence due to diabetes and other impotence. Oral each time 0.005 ~ 0.01g, 3 times a day.
• For severe cases of subcutaneous injection of 2% yohimbine solution 0.5 ~ 1.0ml, 2 ~ 3 times a day, a course of 20 times. Side effects: there are similar to the local anaesthetic effect of cocaine, occasionally palpitations, insomnia, dizziness and other symptoms. It can be relieved after stopping the drug.
• Clinical preparations: yohimbine hydrochloride and commonly used overseas yohimbine-containing compound preparations of yohimbe yuksidol, Xi's yohimbine, Bailuchi yohimbine tablets, Difo yohimbine, Gu's yohimbine, Huo's yohimbine, Knorr yohimbine tablets, yuksite, yohimbine, macrolopin, tolnoctane, and so on. In addition, its similar alkaloids are commonly used as coranine and capitoline.

Production method of Yohimbine Powder

For the treatment of male impotence. It is indicated for the treatment of psychological erectile dysfunction and is less effective in treating organic erectile dysfunction. Yohimbine was the first prescription drug to be approved by the FDA as a treatment for impotence, and its main action comes from blocking the alpha 2 adrenergic receptor on the central nervous system, which can dilate the blood vessels around the genital organs, allowing complete congestion to solve the problem of incomplete erection, with 34%-43% of the users benefiting from it in a 1987 clinical trial.

Yohimbine pure is a white powder, slightly soluble in water, soluble in ethanol, chloroform, hot benzene, slightly soluble in ether. Yohimbine extracted from the bark of the Yohimbine tree in Ghana can effectively improve male sexual dysfunction, it is reported that in the sun-dried Pansinystalia Yohimba bark, the content of mixed yohimbine alkaloids is as high as 6.1% or more, the main part of which is yohimbine, so the plant extracts have a lot of prospects for development.

Among the dosage forms of yohimbine drugs that have been marketed, there are only two dosage forms: tablets and capsules. Yohimbine alkaloids have strong pharmacological effects, small dosage, small molecular weight, and become yohimbine hydrochloride after salting with hydrochloric acid, and their water solubility is greatly improved, and they are easy to penetrate through the cuticle layer of the skin, which is in line with the made of transdermal therapeutic system.

At the same time, Yohimbine also has the effect of clearing wind-heat, lowering liver fire and eliminating swelling and poison. Yunnan Dai early also have application, in Guizhou is often used as antipyretic, analgesic and treatment of snake bites, Guangxi for anti-inflammatory, antipyretic and treatment of typhoid fever, etc..