factory price Ofloxacin powder supplier CAS 82419-36-1

CAS: 82419-36-1

MF: C18H20FN3O4

MW: 361.37

EINECS: 680-263-1

Specification: 99% min Ofloxacin powder

Sample: Ofloxacin Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 KG

Appearance:Colorless needles from ethanol

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Last updated: March 2026

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Ofloxacin Usage and Synthesis.

Oxyfloxacin has the third generation quinolone antibacterial activity, it has good antibacterial effect on Staphylococcus, Streptococcus, Streptococcus pneumoniae, Neisseria gonorrhoeae, Bacillus citriodora, Shigella, Klebsiella pneumoniae, Enterobacteriaceae, Serratiaceae, Aspergillus, Haemophilus influenzae, Fusobacterium indolentum, Campylobacter, etc., and it also has certain antibacterial effects on Pseudomonas aeruginosa and Chlamydia trachomatis, and has the function of anti-TB. It also has the effect of anti-tuberculosis mycobacteria, and can be used with isoniazid and rifampicin in the treatment of tuberculosis. It has strong antibacterial effect on Gram-positive and negative bacteria.

It also has good effect on anaerobic bacteria and Mycoplasma pneumoniae. Antibacterial activity against Aureus, haemolytic streptococcus, etc. is 4-8 times stronger than that of haloperidol.

Clinically, it is mainly used for acute and chronic infections of respiratory tract, pharynx, tonsils, urinary tract including prostate, skin and soft tissues, intestines and otolaryngology caused by sensitive bacteria.

Strategic Applications in Global Markets

In North America and the UK, Ofloxacin is a primary API for treating respiratory tract infections, cellulitis, and urinary tract infections (UTIs). Its high bioavailability (approx. 95%) makes it a preferred choice for oral solid dosage forms.

Due to its excellent tissue penetration, Ofloxacin powder is widely utilized in the European dermo-pharmacy sector for producing sterile eye drops and ear drops to treat bacterial keratitis and otitis media.

In the EU and US veterinary sectors, Ofloxacin is utilized for treating severe skin and soft tissue infections in companion animals (dogs and cats), providing a robust alternative when first-line antibiotics fail.

Drug interactions of Ofloxacin.

Ofloxacin is widely used in combination with other antibiotics, antipyretic and analgesic drugs, antiviral drugs, immunomodulators or developed into compound preparations.

According to the market survey, some provinces and cities have approved more compounded ofloxacin preparations, such as ofloxacin diclofenac sodium injection, ofloxacin hydrochloride levamisole tablets, etc., to expand the antimicrobial spectrum for comprehensive prevention and treatment, especially for other antibiotics with relatively poor efficacy of streptococcus, pneumococcus, mycoplasma, anaerobic bacteria and so on, have a good effect.

Commonly paired with drugs are:

• 1. with astragali polysaccharide, Panax quinquefolium or Qianlong and other antiviral drugs, used for bacterial and viral combined infections;
• 2. with antipyretic and analgesic drugs such as anacin or diclofenac sodium, ketorolac, used for bacterial fever;
• 3. Compounding with herbs such as fritillaria and chaihu for summer fever;
• 4. Compounding with metronidazole for severe anaerobic infections;
• 5. Combined with doxycycline hydrochloride and sulphonamides for haematological protozoa;
• 6. Combined with dysentery and safranin, used for intestinal disorders.

Purity, Standards, and Compliance

To secure B2B contracts with Global Pharmaceutical Manufacturers, documentation and compliance are non-negotiable:

• USP/EP/BP Grade: Our powder is manufactured in compliance with the United States Pharmacopeia, European Pharmacopoeia, and British Pharmacopoeia.

• GMP Certified Production: Synthesized in state-of-the-art facilities with a strict Quality Management System (QMS) and full batch traceability.

• Assay Potency: Guaranteed purity of 98.5% to 101.0% (on a dried basis), ensuring maximum therapeutic efficacy in the final dosage form.

• Regulatory Support: We provide comprehensive documentation including DMF (Drug Master File), CEP (Certificate of Suitability), COA, and MSDS for international registration.

Frequently Asked Questions

Ofloxacin is slightly soluble in water and alcohol, but highly soluble in acidic solutions or glacial acetic acid. This profile is crucial for formulators developing liquid or injectable preparations.

Ofloxacin is a racemic mixture of its "L" and "D" isomers. Levofloxacin is the pure S-enantiomer (L-isomer) of ofloxacin, which typically offers higher potency and lower toxicity, though Ofloxacin remains a highly cost-effective and widely used alternative in many global markets.

It should be stored in a cool, dry place (below 25°C) and protected from direct light. Our industrial-grade, light-resistant fiber drums ensure a 36-month shelf life.

Yes, we provide small-scale quantities for R&D and laboratory testing, alongside bulk commercial quantities for licensed pharmaceutical manufacturers.

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