Theaflavins Raw Materials Theaflavins Powder

CAS:4670-05-7

MF:C29H24O12

MW:564.49

EINECS:/

Specification: 99% min Theaflavins Powder

Sample:Theaflavins powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Red to Dark Red

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Theaflavins Powder Usage and Synthesis.

Theaflavin is a golden-yellow pigment present in black tea as a product of tea fermentation. It is by polyphenols and their derivatives oxidation condensation, black tea tea flavonoids content is generally 0.3% to 1.5%, the colour and aroma of black tea and quality plays a decisive role. Theaflavins are known as the "soft gold" in tea, on the one hand, it is its golden yellow colour in the tea broth, and on the other hand, it is its unique health effects.

Theaflavins have a variety of health effects, such as antiviral, antioxidant, lowering blood lipids, anti-tumour and so on. For those who are healthy, taking theaflavins can play a health role, but it should be noted that any health product should be taken in moderation, not in excess. In addition, patients with stones should drink tea with caution, but whether they can take theaflavins need to consult a doctor's opinion.

Uses and functions of Theaflavins.

1, the efficacy of theaflavin has a lot of, is also very good for the body, theaflavin is taken from the black tea in a pigment, belongs to the fermentation products, has a unique function and biological activity to lower blood lipids. Theaflavin is a pigment taken from black tea, belonging to fermentation products, with unique function and biological activity of lowering blood lipids, and can be effectively combined with cholesterol, fat and other substances to inhibit the absorption and synthesis of blood. After ingested into the body, it can effectively combine with cholesterol, fat, etc., inhibit the absorption and synthesis of such substances in the blood, and play a vital role in the prevention of cardiovascular and cerebrovascular diseases.

It plays a vital role in the prevention of cardiovascular and cerebrovascular diseases.

2, theaflavin has a strong antioxidant function, can form a protective film on the outside of the teeth, reduce dental caries and other dental diseases. Occurrence, and in the clinic is often used as cancer prevention and anti-cancer effective drugs.

Pharmacological Effect of Theaflavins.

Theaflavin inhibited the proliferation and induced the apoptosis of human nasopharyngeal carcinoma CNE2 cells in a time- and concentration-dependent manner, and its mechanism of action may be related to the regulation of cell proliferation and apoptosis gene expression. Theaflavin can reduce serum uric acid in hyperuricemic mice.

The effect of theaflavins on serum uric acid was related to the inhibition of xanthine oxidase activity and the regulation of the expression of mRNA and protein of related anion transporters.

Theaflavin can enhance the sensitivity of cervical cancer cells to cisplatin, and its mechanism may be related to the increase in the expression of apoptosis-related proteins CleavedCaspase3, CleavedCaspase9 and PARP, and the inhibition of the expression of NF-κB signalling pathway-related proteins p-IκBα, p-NF-κB and p-Akt.

Theaflavins can effectively delay the inflammatory degeneration process of rat chondrocytes by enhancing the activity of chondrocyte synthesis factors, attenuating the activity of catabolic factors and inhibiting the cellular inflammatory response, and have a certain protective effect on inflammatory chondrocytes.

Preparation of Bulk Theaflavins Powder.

Weighing 100g of tea leaves, adding 1000ml of deionised water (90 ℃) extraction for 30min, remove the extract; then add 500ml of deionised water (90 ℃) extraction for 30min; combined with the extract, 300 mesh filter cloth filtration, 0.05um ceramic membrane treatment, to get theaflavin microfiltration solution.

The theaflavin microfiltrate was pumped from the heavy-phase inlet into a two-stage tandem centrifugal extractor, and at the same time, ethyl acetate solution with 1/2 the volume of the theaflavin microfiltrate material was pumped into the two tandem centrifugal extractors with a rotational speed of 3000 rpm, and the light-phase outlet solution (i.e., ester-phase solution) was collected, and then processed with low-temperature vacuum concentration at 40 ℃, and spray drying to obtain the theaflavin extracts, which had a purity of theaflavin of 21.35%.